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1. IN201741002329 - DIETARY SUPPLEMENTS FOR INHIBITING PDE5 AND INCREASING CGMP LEVELS

Office
India
Application Number 201741002329
Application Date 20.01.2017
Publication Number 201741002329
Publication Date 27.07.2018
Publication Kind A
IPC
A61k 36/00
A61K 36/185
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
A61K 36/38
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
38Clusiaceae, Hypericaceae or Guttiferae (Hypericum or Mangosteen family), e.g. common St. Johnswort
Applicants LAILA NUTRACEUTICALS
Inventors GOKARAJU, Ganga Raju
GOKARAJU, Rama Raju
GOLAKOTI, Trimurtulu
BHUPATHIRAJU, Kiran
GOKARAJU, Venkata Kanaka Ranga Raju
SENGUPTHA, Krishanu
ALLURI, Venkata Krishna Raju
Title
(EN) DIETARY SUPPLEMENTS FOR INHIBITING PDE5 AND INCREASING CGMP LEVELS
Abstract
(EN) The invention discloses synergistic compositions comprising extracts, fractions or pure compounds derived from at least two herbs selected from Punica granatum, Mangifera indica and Garcinia mangostana for inhibiting the expression/production/activity of Phosphodiesterase 5 (PDE5) enzyme or for increasing cGMP levels in a male subject. The invention further discloses a method of inhibiting the expression/production/activity of Phosphodiesterase 5 (PDE5) enzyme, increasing cGMP levels and sexual arousal, treating/ alleviating various aspects of male sexual dysfunction or impotence such as erectile dysfunction, loss of libido, or orgasm/ejaculation disorders in a male subject by using a suitable dose of synergistic composition comprising extracts, fractions or pure compounds derived from at least two herbs selected from Punica granatum, Mangifera indica and Garcinia mangostana.
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