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1. IN201618040221 - HUMANIZED L243 ANTIBODIES

Office India
Application Number 201618040221
Application Date 24.11.2016
Publication Number 201618040221
Publication Date 21.04.2017
Publication Kind A
IPC
C12N 15/13
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
11DNA or RNA fragments; Modified forms thereof
12Genes encoding animal proteins
13Immunoglobulins
Applicants Immunomedics, Inc.
Inventors GOLDENBERG, David M.
HANSEN, Hans J.
QU, Zhengxing
CHANG, Chien-Hsing
Priority Data 60/657,695 03.03.2005 US
Title
(EN) HUMANIZED L243 ANTIBODIES
Abstract
(EN)
Humanized antibodies are provided that specifically bind HLA-DR. The antibodies recognize the epitope recognized by the murine monoclonal antibody L243. Processes for preparing such antibodies, pharmaceutical compositions containing such antibodies, and clinical therapuetic and diagnostic, as well as research-related uses for such antibodies, are provided.