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1. (IN201647039563) 5 CHLORO 2 DIFLUOROMETHOXYPHENYL PYRAZOLOPYRIMIDINE COMPOUNDS WHICH ARE JAK INHIBITORS

Office : India
Application Number: 201647039563 Application Date: 21.11.2016
Publication Number: 201647039563 Publication Date: 09.12.2016
Publication Kind : A
Prior PCT appl.: Application Number:PCTEP2015061350 ; Publication Number:WO2015177326 Click to see the data
IPC:
C07D 48/04
A61K 31/519
A61P 11/06
[IPC code unknown for C07D 48/04]
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
495
having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505
Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
519
ortho- or peri-condensed with heterocyclic rings
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11
Drugs for disorders of the respiratory system
06
Antiasthmatics
Applicants: F. HOFFMANN-LA ROCHE AG
Inventors: ZAK, Mark Edward
RAY, Nicholas Charles
GOODACRE, Simon Charles
MENDONCA, Rohan
KELLAR, Terry
CHENG, Yun Xing
LI,Wei
YUEN, Po wai
Priority Data: PCT/CN2015/077176 22.04.2015 CN
62/002547 23.05.2014 US
62/101234 08.01.2015 US
62/130098 09.03.2015 US
Title: (EN) 5 CHLORO 2 DIFLUOROMETHOXYPHENYL PYRAZOLOPYRIMIDINE COMPOUNDS WHICH ARE JAK INHIBITORS
Abstract:
(EN) Compounds of Formula (00A) and methods of use as Janus kinase inhibitors are described herein. Claimed uses are the treatment of inflammation and asthma.
Also published as:
CA2948589SG11201609830RIL248661CN106459039EP3145929AU2015261812
US20170145020JP2017516850KR1020170005870PH1/2016/502099ID2017/12804EA201692338
MYPI 2016002027US20180305355CR20160539WO/2015/177326