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1. IN3083/MUMNP/2015 - N PHENYL CARBOXAMIDE DERIVATIVES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B

Office
India
Application Number 3083/MUMNP/2015
Application Date 27.10.2015
Publication Number 3083/MUMNP/2015
Publication Date 22.07.2016
Grant Number 320783
Grant Date 18.09.2019
Publication Kind B
IPC
C07D 405/12
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
405Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
02containing two hetero rings
12linked by a chain containing hetero atoms as chain links
C07D 409/12
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
409Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
02containing two hetero rings
12linked by a chain containing hetero atoms as chain links
C07D 487/08
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
487Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/-C07D477/183
02in which the condensed system contains two hetero rings
08Bridged systems
Applicants JANSSEN SCIENCES IRELAND UC
Inventors VANDYCK Koen
HACHÉ Geerwin Yvonne Paul
LAST Stefaan Julien
RABOISSON Pierre Jean Marie Bernard
Priority Data 13162131.0 03.04.2013 EP
Title
(EN) N PHENYL CARBOXAMIDE DERIVATIVES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B
Abstract
(EN)
1234Inhibitors of HBV replication of Formula (I) including stereochemically isomeric forms and salts hydrates solvates thereof wherein X R R R and R have the meaning as defined herein. The present invention also relates to processes for preparing said compounds pharmaceutical compositions containing them and their use alone or in combination with other HBV inhibitors in HBV therapy.