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1. IN393/CHENP/2013 - PROCESS FOR CINACALCET HYDROCHLORIDE

Office
India
Application Number 393/CHENP/2013
Application Date 17.01.2013
Publication Number 393/CHENP/2013
Publication Date 20.02.2015
Publication Kind A
IPC
C07C 21/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
21Acyclic unsaturated compounds containing halogen atoms
Applicants HETERO RESEARCH FOUNDATION
Inventors PARTHASARADHI REDDY Bandi
RATHNAKAR REDDY Kura
MURALIDHARA REDDY Dasari
RAJI REDDY Rapolu
MUKUNDA REDDY Jambula
VAMSI KRISHNA Bandi
Title
(EN) PROCESS FOR CINACALCET HYDROCHLORIDE
Abstract
(EN) 3 [3 (Trifluoromethyl)phenyl]propionaldehyde is a key intermediate for the preparation of cinacalcet hydrochloride. The present invention provides a novel process for the preparation of 3 [3 (trifluoromethyl)phenyl]propionaldehyde. The present invention also provides an improved process for preparation of cinacalcet hydrochloride in high yields. The present invention further provides a process for purification of cinacalcet hydrochloride.
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