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1. IN886/CHENP/2013 - “A method of producing a derivative of Dolutegravir or a derivative of Cabotegravir”

Office
India
Application Number 886/CHENP/2013
Application Date 04.02.2013
Publication Number 886/CHENP/2013
Publication Date 12.12.2014
Grant Number 319709
Grant Date 03.09.2019
Publication Kind B
IPC
C07D 498/14
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
498Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
12in which the condensed system contains three hetero rings
14Ortho-condensed systems
A61K 31/536
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
535having six-membered rings with at least one nitrogen and at least one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
536ortho- or peri-condensed with carbocyclic ring systems
A61P 31/18
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
14for RNA viruses
18for HIV
Applicants Shionogi & Co. Ltd.
Inventors SUMINO, Yukihito
OKAMOTO, Kazuya
MASUI, Moriyasu
YAMADA, Daisuke
IKARASHI, Fumiya
Priority Data 2010175899 05.08.2010 JP
2010277713 14.12.2010 JP
Title
(EN) “A method of producing a derivative of Dolutegravir or a derivative of Cabotegravir”
Abstract
(EN) x1d2d4d6dA process for preparing a compound represented by formula (Y1) or (Y2) [wherein R is an optionally substituted carbocyclyl lower alkyl group or the like] using a novel process for preparing a pyridone derivative represented by formula (X4) [wherein R is hydrogen halogen or the like; R is hydrogen a lower alkyl group or the like said lower alkyl group being optionally substituted with one or more selected from substituent group E; R is a lower alkyl group or the like said lower alkyl group being optionally substituted with one or more selected from substituent group E; and R is a lower alkyl group or the like said lower alkyl group being optionally substituted with one or more selected from substituent group E].