Processing

Please wait...

Settings

Settings

1. IN5183/DELNP/2011 - COMPOSITIONS OF PROTEIN RECEPTOR TYROSINE KINASE INHIBITORS

Office India
Application Number 5183/DELNP/2011
Application Date 05.07.2011
Publication Number 5183/DELNP/2011
Publication Date 04.10.2013
Publication Kind A
IPC
[IPC code unknown for C07D 48/04]
C07D 48/04
Applicants VM PHARMA LLC
Inventors WU, JAY JIE-QIANG
WANG, LING
Priority Data 61/120,827 08.12.2008 US
Title
(EN) COMPOSITIONS OF PROTEIN RECEPTOR TYROSINE KINASE INHIBITORS
Abstract
(EN)
The present invention relates to novel synthetic substituted heterocyclic compounds and pharmaceutical compositions containing the same that are capable of inhibiting or antagonizing a family of receptor tyrosine kinases, Tropomysosin Related Kinases (Trk), in particular the nerve growth factor (NGF) receptor, TrkA. The invention further concerns the use of such compounds in the treatment and/or prevention of pain, cancer, restenosis, atherosclerosis, psoriasis, thrombosis, or a disease, disorder or injury relating to dysmyelination or demyelination or the disease or disorder associated with abnormal activities of NGF recptor TrkA.