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1. (IN5232/DELNP/2011) COMPOSITIONS AND METHODS TO PREVENT CANCER WITH CUPREDOXINS

Office : India
Application Number: 5232/DELNP/2011 Application Date: 07.07.2011
Publication Number: 5232/DELNP/2011 Publication Date: 10.08.2012
Publication Kind : A
Prior PCT appl.: Application Number:PCTUS2009068492 ; Publication Number: Click to see the data
IPC:
C07K /
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
Applicants: CDG THERAPEUTICS  INC.
Inventors: Tapas DAS GUPTA
Rajendra G. MEHTA
Rajeshwari MEHTA
Craig BEATTIE
Priority Data: 12/337,167 17.12.2008 US
Title: (EN) COMPOSITIONS AND METHODS TO PREVENT CANCER WITH CUPREDOXINS
Abstract:
(EN) The present invention relates to compositions and methods comprising chemopreventive agents that may be cupredoxin(s) or variants, derivatives and structural equivalents of cupredoxins, and at least one other chemopreventive agent. Specifically, these compositions may comprise azurin from Pseudomonas aeruginosa, and/or the 50-77 residue region of azurin (p28). The at least one other chemopreventive agent may comprise an antiestrogen such as Tamoxifen. The compositions of the invention may be used to prevent the development of premalignant lesions in mammalian cells, tissues and animals, and thus prevent cancer.
Also published as:
IL213657SG172195EP2379097JP2012512259CN102316887CA2747404
KR1020110126595AU2009333174WO/2010/078042