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1. IN1788/MUMNP/2008 - IMMUNOMODULATERY AND ANTI-TUMOR PEPTIDES

Office
India
Application Number 1788/MUMNP/2008
Application Date 20.08.2008
Publication Number 1788/MUMNP/2008
Publication Date 03.10.2008
Grant Number 252492
Grant Date 25.05.2012
Publication Kind B
IPC
C07K 14/435
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
Applicants CENTRO DE INGENIERÍA GENÉTICA BIOTECNOLOGÍA
Inventors AGUERRA VALLESPÍ, MARIBEL
TORRÉNS MADRAZO, ISIS DEL CARMEN
REYES ACOSTA, OSVALDO
GARAY PEREZ, HILDA ELISA
GUILLÉN NIETO, GERARDO, ENRIQUE
ACEVEDO CASTRO, BORIS ERNESTO
UBIETA GÓMEZ, RAIMUNDO
Priority Data 20060047 24.02.2006 CU
Title
(EN) IMMUNOMODULATERY AND ANTI-TUMOR PEPTIDES
Abstract
(EN)
The invention relates to the development of peptides originating from sequence HYRIKPTFRRLKWKKYKGKFW, into which amino acid substitutions have been introduced, which guarantee the dissociation of the lipopolysaccharide-binding capacity and potentiate the anti-tumour and immunomodulatory effect. Said peptides and combinations thereof can be used in the treatment of cancer, as well as in synergism with other standard therapies.