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1. (IN687/CHENP/2008) PERCUTANEOUSLY ABSORPTIVE OPHTHALMIC PREPARATION COMPRISING EPINASTINE

Office : India
Application Number: 687/CHENP/2008 Application Date: 08.02.2008
Publication Number: 687/CHENP/2008 Publication Date: 28.11.2008
Publication Kind : A
Prior PCT appl.: Application Number:PCTJP2006314005 ; Publication Number:WO2007007851A1 Click to see the data
IPC:
A61K 9/70
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
70
Web, sheet or filament bases
Applicants: SENJU PHARMACEUTICAL CO LTD
Inventors: ISOWAKI, AKIHARU
NAKAJIMA, TOMOKO
OHTORI, AKIRA
Priority Data: 60/697,369 08.07.2005 US
Title: (EN) PERCUTANEOUSLY ABSORPTIVE OPHTHALMIC PREPARATION COMPRISING EPINASTINE
Abstract:
(EN) The present invention provides a percutaneous absorptive preparation for preventing or treating allergic eye disease, which comprises epinastine or a salt thereof as an active ingredient. In addition, the present invention provides a method for preventing or treating allergic eye disease, which comprises applying a percutaneously absorptive preparation comprising epinastine or a salt thereof to the skin surface including the skin surface of an eyelid, thereby causing transfer of a therapeutically effective amount of epinastine or a salt thereof from the preparation to an anterior ocular segment through the skin of the eyelid rather than a systemic blood flow. The present preparation can exert a pharmacological effect over a prolonged period by a single application, as compared to conventional preparations such as eye drops.
Also published as:
KR1020080034916EP1901724JP2009500397US20090143359CN101217948WO/2007/007851