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1. (IN5286/CHENP/2007) SELF-BUFFERING PROTEIN FORMULATIONS

Office : India
Application Number: 5286/CHENP/2007 Application Date: 21.11.2007
Publication Number: 5286/CHENP/2007 Publication Date: 25.01.2008
Publication Kind : A
Prior PCT appl.: Application Number:PCTUS2006022599 ; Publication Number:WO2006138181A2 Click to see the data
IPC:
A61K 39/395
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
Applicants:
Inventors:
Priority Data:
Title: (EN) SELF-BUFFERING PROTEIN FORMULATIONS
Abstract:
(EN) The invention herein described, provides, among other things, self-buffering protein formulations. Particularly, the invention provides self-buffering pharmaceutical protein formulations that are suitable for veterinary and human medical use. The self-buffering protein formulations are substantially free of other buffering agents, stably maintain pH for the extended time periods involved in the distribution and storage of pharmaceutical proteins for veterinary and human medical use. The invention further provides methods for designing, making, and using the formulation. In addition to other advantages, the formulations avoid the disadvantages associated with the buffering agents conventionally used in current formulations of proteins for pharmaceutical use. The invention in these and other respects can be productively applied to a wide variety of proteins and is particularly useful for making and using self-buffering formulations of pharmaceutical proteins for veterinary and medical use, especially, in particular, for the treatment of diseases in human subjects.
Also published as:
MXMX/a/2007/015476KR1020080031684IL188102SG162788EP1909831ZA2008/00338
JP2008543839US20080311078BRPI0611901JP2013047261CN101217979CA2610839
EA200800050JP2016053061AU2006259664AU2012272950AU2015242973AU2017202889
JP2018048196EP3351269WO/2006/138181