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1. IN4031/KOLNP/2007 - PIPERIDINYL SUBSTITUTED CYCLOHEXANE-1, 4-DIAMINES

Office India
Application Number 4031/KOLNP/2007
Application Date 22.10.2007
Publication Number 4031/KOLNP/2007
Publication Date 25.01.2008
Publication Kind A
IPC
A61K 31/454
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
44Non-condensed pyridines; Hydrogenated derivatives thereof
445Non-condensed piperidines, e.g. piperocaine
4523containing further heterocyclic ring systems
454containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
Applicants JANSSEN PHARMACEUTICA N.V.
Inventors GEORGE CHIU
SHENGJIAN LI
PETER J. CONNOLLY
VIRGINIA L. PULITO
JINGCHUN LIU
STEVEN A. MIDDLETON
Priority Data 60/664,302 22.03.2005 US
Title
(EN) PIPERIDINYL SUBSTITUTED CYCLOHEXANE-1, 4-DIAMINES
Abstract
(EN)
The present invention relates to piperidine substituted cyclohexane-1,4-diaminecompounds of Formula (I) and pharmaceutical acceptable forms thereof, asala/ald adrenoreceptor modulators for the treatment of benign prostatic hypetrophy and lower urinary tract symptoms. The present invention also relates to pharmaceutical compositions comprising said new compounds, new process to prepare these new compounds and new uses as a medicine as well as method oftreatments.