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1. IL111402 - SUSPENSION OF LOTEPREDNOL ETABONATE FOR EAR, EYE OR NOSE TREATMENT

Office
Israel
Application Number 111402
Application Date 25.10.1994
Publication Number 111402
Publication Date 06.12.2000
Publication Kind B
CPC
A61K 9/0043
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
0012Galenical forms characterised by the site of application
0043Nose
A61K 9/0048
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
0012Galenical forms characterised by the site of application
0048Eye, e.g. artificial tears
A61K 31/56
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives, e.g. steroids
A61K 31/715
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
A61K 31/74
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
74Synthetic polymeric materials
A61K 31/79
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
74Synthetic polymeric materials
785Polymers containing nitrogen
787containing heterocyclic rings having nitrogen as a ring hetero atom
79Polymers of vinyl pyrrolidone
Applicants PHARMOS CORPORATION
Agents ד" ר וב ושות'
Priority Data 08142743 25.10.1993 US
Title
(EN) SUSPENSION OF LOTEPREDNOL ETABONATE FOR EAR, EYE OR NOSE TREATMENT
(HE) תרחיף של לוטפרדנול אטבונט לטיפול באוזן בעין או באף
Abstract
(EN) Composition for opthalmic or otolarynological anti-inflammatory use comprising: (A) a corticosteroid having a particle size of 0.1 to 30 microns in diameter in an amount of about 0.2 to 2% by weight; (B) a nonionic polymer in an aqueous medium; (C) a nonionic surface active agent in an amount sufficient to retain the corticosteroid in suspension; and (D) a nonionic tonicity agent in an amount sufficient to achieve isotonicity wherein the molar ratio of (A) : (B) : (C) is between about 1:20:1 and about 1:0.01:0.5. 1654 כ" ג בתמוז התש" ס - July 26, 2000