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1. ID042.402 - TURUNAN SULFONILPIPERIDINA YANG MENGANDUNG MOIETAS ALKENIL ATAU ALKUNIL UNTUK DIPAKAI SEBAGAI PENGHAMBAT MATRIKS METALOPROTEINASE

Office Indonesia
Application Number W00200500086
Application Date 09.07.2003
Publication Number 042.402
Publication Date 31.03.2005
Publication Kind A
IPC
A61K 31/445
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
44Non-condensed pyridines; Hydrogenated derivatives thereof
445Non-condensed piperidines, e.g. piperocaine
A61P 37/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37Drugs for immunological or allergic disorders
C07D 211/96
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
211Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
92with a hetero atom directly attached to the ring nitrogen atom
96Sulfur atom
C07D 239/26
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
239Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
02not condensed with other rings
24having three or more double bonds between ring members or between ring members and non-ring members
26with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
C07D 401/12
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
401Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
02containing two hetero rings
12linked by a chain containing hetero atoms as chain links
Applicants ASTRAZENECA AB
Agents Drs. J.B. LUMENTA, S.H., L.LM.
Title
(ID) TURUNAN SULFONILPIPERIDINA YANG MENGANDUNG MOIETAS ALKENIL ATAU ALKUNIL UNTUK DIPAKAI SEBAGAI PENGHAMBAT MATRIKS METALOPROTEINASE
Abstract
(ID)
Suatu senyawa formula (1) dimana B adalah sebagai pilihan disustitusi C2-4alkinil atau C2-4alkunil; sangat berguna dalam penghambatan satu atau lebih metaloproteinase-metaloprotei nase dan khususnya TACE.