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1. GEP20176609B - COMPOSITION FOR NASAL APPLICATION WITH IMPROVED STABILITY

Office
Georgia
Application Number AP 2012 13539
Application Date 25.09.2012
Publication Number P20176609B
Publication Date 25.01.2017
Publication Kind B
IPC
A61K 31/415
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
41having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
4151,2-Diazoles
A61K 31/164
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
16Amides, e.g. hydroxamic acids
164of a carboxylic acid with an aminoalcohol, e.g. ceramides
A61K 31/4174
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
41having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
41641,3-Diazoles
4174Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
A61K 31/525
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
519ortho- or peri-condensed with heterocyclic rings
525Isoalloxazines, e.g. riboflavins, vitamin B2
A61P 11/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
02Nasal agents, e.g. decongestants
Applicants MARIA CLEMENTINE MARTIN KLOSTERFRAU VERTRIEBSGESEL- LSCHAFT MBH
Inventors Harald GREVE
Agents Tamar Kochlamazashvili
Priority Data 10 2011 122 588.2 30.12.2011 DE
102012005452 20.03.2012 DE
Title
(EN) COMPOSITION FOR NASAL APPLICATION WITH IMPROVED STABILITY
Abstract
(EN) There is represent pharmaceutical composition with improved stability for local usage at rhinitis treatment, wherein composition contains: a) Xylometazoline or physiologically acceptable salt thereof, in amount of 0.02-1.0 mass%; b) Panthenol (dexpanthenol) in amount of 0.5-8 mass%; and c) Benzalkonium chloride as conservent and/or disinfection means, in amount of 0.001-10 mass%; At that, composition stability is provided by pH-value regulation from 5.2 to 5.9 and/or by maintaining constant value by means of phosphate buffer system. Claims: 6 independent 5 dependent Fig.: 4
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