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1. GB2485345 - Optical coherence tomography scanning to identify a region of interest in a sample

Office United Kingdom
Application Number 201018743
Application Date 05.11.2010
Publication Number 2485345
Publication Date 22.12.2010
Publication Kind A
IPC
A61B 5/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes; Identification of persons
A61B 3/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
3Apparatus for testing the eyes; Instruments for examining the eyes
10Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions
A61B 3/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
3Apparatus for testing the eyes; Instruments for examining the eyes
10Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions
12for looking at the eye fundus, e.g. ophthalmoscopes
G01B 11/22
GPHYSICS
01MEASURING; TESTING
BMEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
11Measuring arrangements characterised by the use of optical means
22for measuring depth
G01N 21/47
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
17Systems in which incident light is modified in accordance with the properties of the material investigated
47Scattering, i.e. diffuse reflection
CPC
G01N 21/17
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
17Systems in which incident light is modified in accordance with the properties of the material investigated
A61B 5/0066
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
0059using light, e.g. diagnosis by transillumination, diascopy, fluorescence
0062Arrangements for scanning
0066Optical coherence imaging
A61B 5/445
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
44Detecting, measuring or recording for evaluating the integumentary system, e.g. skin, hair or nails
441Skin evaluation, e.g. for skin disorder diagnosis
445Evaluating skin irritation or skin trauma, e.g. rash, eczema, wound, bed sore
A61B 5/4552
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
45For evaluating or diagnosing the musculoskeletal system or teeth
4538Evaluating a particular part of the muscoloskeletal system or a particular medical condition
4542Evaluating the mouth, e.g. the jaw
4552Evaluating soft tissue within the mouth, e.g. gums or tongue
A61B 3/102
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
3Apparatus for testing the eyes; Instruments for examining the eyes
10Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
102for optical coherence tomography [OCT]
A61B 3/1225
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
3Apparatus for testing the eyes; Instruments for examining the eyes
10Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
12for looking at the eye fundus, e.g. ophthalmoscopes
1225using coherent radiation
Applicants QUEEN MARY & WESTFIELD COLLEGE
SEC DEP FOR BUSINESS INNOVATION & SKILLS
Inventors TOMLINS PETER
ADEGUN OLUYORI KUTULOLA
FORTUNE FARIDA
Priority Data 201018743 05.11.2010 GB
Title
(EN) Optical coherence tomography scanning to identify a region of interest in a sample
Abstract
(EN)
The present invention provides a method of identifying a region of interest in a sample. The method comprises obtaining one or more optical coherence tomography (OCT) axial scans at one or more locations over the sample surface; for each axial scan, determining an integrated total of OCT intensity over the depth of the scan, and determining an attenuation depth into the sample at which a predetermined fraction of the integrated total is reached; and determining from the one or more attenuation depths a region of interest in the sample. Generally, the method does not depend on the accuracy (or inaccuracy) of any particular scientific model of scattering and attenuation. The method / apparatus may be applied to biological or non-biological samples.