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1. FR2908408 - NOUVEAUX DERIVES DE LA TRIPHENYLAMINE UTILIES COMME FLUOROPHORES EN BIOLOGIE, NOTAMMENT POUR LA MICROSCOPIE BIPHOTONIQUE

Office
France
Application Number 0654837
Application Date 10.11.2006
Publication Number 2908408
Publication Date 16.05.2008
Grant Number 2908408
Grant Date 30.01.2009
Publication Kind B1
IPC
C07D 213/38
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
213Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
02having three double bonds between ring members or between ring members and non-ring members
04having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
24with substituted hydrocarbon radicals attached to ring carbon atoms
36Radicals substituted by singly-bound nitrogen atoms
38having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
A61K 31/4425
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
44Non-condensed pyridines; Hydrogenated derivatives thereof
4425Pyridinium derivatives, e.g. pralidoxime, pyridostigmine
A61P 43/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43Drugs for specific purposes, not provided for in groups A61P1/-A61P41/108
CPC
A61P 43/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
C07D 213/38
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
213Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
02having three double bonds between ring members or between ring members and non-ring members
04having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
24with substituted hydrocarbon radicals attached to ring carbon atoms
36Radicals substituted by singly-bound nitrogen atoms
38having only hydrogen, hydrocarbon radicals attached to the substituent nitrogen atom
C09B 23/00
CCHEMISTRY; METALLURGY
09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
BORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES ; , e.g. PIGMENTS; MORDANTS; LAKES
23Methine or polymethine dyes, e.g. cyanine dyes
Applicants COMMISSARIAT ENERGIE ATOMIQUE
Inventors ALLAIN CLEMENCE
CHARRA FABRICE
FIORINI DEBUISSCHERT CELINE
LARTIA REMY
TEULADE FICHOU MARIE PAULE
Priority Data 0654837 10.11.2006 FR
Title
(FR) NOUVEAUX DERIVES DE LA TRIPHENYLAMINE UTILIES COMME FLUOROPHORES EN BIOLOGIE, NOTAMMENT POUR LA MICROSCOPIE BIPHOTONIQUE
Abstract
(FR)
L'invention se rapporte à de nouveaux dérivés de la triphénylamine utiles comme fluorophores, notamment pour la microscopie biphotonique en biologie.Elle se rapporte également à des compositions contenant ces dérivés, à l'utilisation de ces compositions ainsi que des dérivés eux-mêmes pour le marquage de molécules biologiques (ou "biomolécules") telles que les acides nucléiques, les oligonucléotides, les protéines, les polypeptides, les plasmides, etc, en vue de leur observation notamment par microscopie biphotonique, et à des biomolécules marquées par lesdits dérivés.Applications : imagerie biologique et médicale (recherche fondamentale pour l'étude structurelle ou fonctionnelle des systèmes biologiques, recherche appliquée à visée clinique ou thérapeutique, diagnostic et dépistage médical, ...) .