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1. FR3004180 - NOUVEAUX DERIVES DE CHALCONE PRESENTANT UNE ACTIVITE ANTI-ALLERGIQUE

Office
France
Application Number 1353091
Application Date 05.04.2013
Publication Number 3004180
Publication Date 10.10.2014
Grant Number 3004180
Grant Date 26.06.2015
Publication Kind B1
IPC
C07D 211/18
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
211Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
04with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
06having no double bonds between ring members or between ring members and non-ring members
08with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
18with substituted hydrocarbon radicals attached to ring carbon atoms
A61K 31/4418
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
44Non-condensed pyridines; Hydrogenated derivatives thereof
4418having a carbocyclic ring directly attached to the heterocyclic ring, e.g. cyproheptadine
A61P 37/08
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37Drugs for immunological or allergic disorders
08Antiallergic agents
CPC
A61P 1/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
A61P 11/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
02Nasal agents, e.g. decongestants
A61P 11/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
06Antiasthmatics
A61P 17/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17Drugs for dermatological disorders
A61P 19/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
19Drugs for skeletal disorders
02for joint disorders, e.g. arthritis, arthrosis
A61P 27/14
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
27Drugs for disorders of the senses
02Ophthalmic agents
14Decongestants or antiallergics
Applicants UNIV CLAUDE BERNARD LYON
HOSPICES CIVILS LYON
CENTRE NAT RECH SCIENT
Inventors DUMONTET CHARLES
BOUMENDJEL AHCENE
MONNERET GUILLAUME
Priority Data 1353091 05.04.2013 FR
Title
(FR) NOUVEAUX DERIVES DE CHALCONE PRESENTANT UNE ACTIVITE ANTI-ALLERGIQUE
Abstract
(FR)
La présente invention concerne les composés de formule (I) : dans laquelle : - R2, R4 et R6, identiques ou différents, représentent un atome d'hydrogène, chlore, brome, iode ou fluor, ou un groupe -OH ou -O-alkyle comprenant de 1 à 6 atomes de carbone ; - R2' et R4', identiques ou différents, représentent un atome d'hydrogène, ou un groupe -OH ou -O-alkyle comprenant de 1 à 6 atomes de carbone ; - n est égal à 1, 2, 3 ; - X = CH2, 0, S ou N(R7); et - R7 représente un atome d'hydrogène ou un groupe alkyle comprenant de 1 à 6 atomes de carbone ; ainsi que leurs hydrates, solvats et sels pharmaceutiquement acceptables.