ES2240051 DERIVADOS DE 2-AMINO-BENZOXAZINA PARA EL TRATAMIENTO DE LA OBESIDAD.

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Application Number E00900081

Application Date 06.01.2000

Publication Number 2240051

Publication Date 16.10.2005

Publication Kind T3

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Applicants ALIZYME THERAPEUTICS LIMITED

Inventors HODSON, HAROLD FRANCIS
DOWNHAM, ROBERT, CAMBRIDGE DISCOVERY CHEMISTRY
MITCHELL, TIMOTHY J., CAMBRIDGE DISCOVERY CHEM.
CARR, BEVERLEY JANE
DUNK, CHRISTOPHER ROBERT, ALIZYME THERAPEUTICS LTD
PALMER, RICHARD M. J., ALIZYME THERAPEUTICLIMITED

Priority Data 99004160 08.01.1999 GB

Title

(ES) DERIVADOS DE 2-AMINO-BENZOXAZINA PARA EL TRATAMIENTO DE LA OBESIDAD.

Abstract

(ES) El uso de un compuesto que comprende la **fórmula** o una sal farmacéuticamente aceptable, éster o amida del mismo; en la fabricación de un medicamento para el tratamiento de afecciones que requieren la inhibición de un enzima cuyo modo de acción preferido es catalizar la hidrólisis de una funcionalidad éster, siendo dicha afección obesidad o un trastorno relacionado con la obesidad.

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
J	CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
3	Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms

A	HUMAN NECESSITIES
23	FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
L	FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D91; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
1	Foods or foodstuffs; Their preparation or treatment
29	Modifying nutritive qualities of foods; Dietetic products
30	containing additives

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
J	CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
3	Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
02	into the form of powders

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
J	CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
3	Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
06	into the form of pills, lozenges or dragees

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
J	CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
3	Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
07	into the form of capsules or similar small containers for oral use

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1. ES2240051 - DERIVADOS DE 2-AMINO-BENZOXAZINA PARA EL TRATAMIENTO DE LA OBESIDAD.

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients
33	Heterocyclic compounds
395	having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
535	having six-membered rings with at least one nitrogen and at least one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
536	ortho- or peri-condensed with carbocyclic ring systems

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
P	SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1	Drugs for disorders of the alimentary tract or the digestive system

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
C	ACYCLIC OR CARBOCYCLIC COMPOUNDS
271	Derivatives of carbamic acid, i.e. compounds containing any of the groups the nitrogen atom not being part of nitro or nitroso groups
06	Esters of carbamic acids
08	having oxygen atoms of carbamate groups bound to acyclic carbon atoms
26	with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring
28	to a carbon atom of a non-condensed six-membered aromatic ring

C	CHEMISTRY; METALLURGY
12	BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N	MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9	Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
99	Enzyme inactivation by chemical treatment