ES2878145 Métodos para el tratamiento del cáncer pancreático que comprenden paclitaxel y gemcitabina

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Spain

Application Number 14737791

Application Date 10.01.2014

Publication Number 2878145

Publication Date 18.11.2021

Publication Kind T3

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Applicants Abraxis BioScience, LLC

Inventors DESAI, Neil P.
RENSCHLER, Markus

Agents ELZABURU, S.L.P

Priority Data 13794480 11.03.2013 US
201361751820 P 11.01.2013 US
201361752355 P 14.01.2013 US

Title

(ES) Métodos para el tratamiento del cáncer pancreático que comprenden paclitaxel y gemcitabina

Abstract

(ES) Una composición que comprende nanopartículas que comprenden paclitaxel y una albúmina para su uso en un método para tratar cáncer pancreático metastásico o avanzado localmente en un individuo que lo necesita, en donde el método comprende administrar la comprende con gemcitabina, y en donde el individuo se selecciona para el tratamiento sobre la base de (i) tener cáncer pancreático en la localización primaria en la cabeza del páncreas, y/o (ii) tener un nivel sérico de CA 19-9 que es >=59 x ULN (Límite Superior del Normal).

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients
33	Heterocyclic compounds
335	having oxygen as the only ring hetero atom, e.g. fungichromin
337	having four-membered rings, e.g. taxol

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients
70	Carbohydrates; Sugars; Derivatives thereof
7042	Compounds having saccharide radicals and heterocyclic rings
7052	having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
706	containing six-membered rings with nitrogen as a ring hetero atom
7064	containing condensed or non-condensed pyrimidines
7068	having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
P	SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31	Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
P	SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35	Antineoplastic agents
04	specific for metastasis

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45	Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
06	Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

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1. ES2878145 - Métodos para el tratamiento del cáncer pancreático que comprenden paclitaxel y gemcitabina

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9	Medicinal preparations characterised by special physical form
48	Preparations in capsules, e.g. of gelatin, of chocolate
50	Microcapsules ; having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
51	Nanocapsules; Nanoparticles;
5107	Excipients; Inactive ingredients
513	Organic macromolecular compounds; Dendrimers
5169	Proteins, e.g. albumin, gelatin

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9	Medicinal preparations characterised by special physical form
48	Preparations in capsules, e.g. of gelatin, of chocolate
50	Microcapsules ; having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
51	Nanocapsules; Nanoparticles;
5107	Excipients; Inactive ingredients
513	Organic macromolecular compounds; Dendrimers
5169	Proteins, e.g. albumin, gelatin

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9	Medicinal preparations characterised by special physical form
0012	Galenical forms characterised by the site of application
0019	Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner