ES2848150 Un ligando del receptor de adenosina A3 para su uso en el tratamiento de la acumulación de grasa ectópica

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Application Number 16806299

Application Date 22.11.2016

Publication Number 2848150

Publication Date 05.08.2021

Publication Kind T3

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CPC

Applicants Can-Fite Biopharma Ltd.

Inventors FISHMAN, Pnina
COHEN, Shira

Agents González Peces Gustavo Adolfo

Priority Data 242723 23.11.2015 IL

Title

(ES) Un ligando del receptor de adenosina A3 para su uso en el tratamiento de la acumulación de grasa ectópica

Abstract

(ES) Un agonista del receptor de adenosina A3 (A3AR) para su uso en la reducción de la acumulación de lípidos en un tejido hepático de un sujeto que tiene la enfermedad del hígado graso no alcohólico (NAFLD), en el que dicho agonista del A3AR se selecciona del grupo que consiste en N6-2-(4-aminofenil)etil adenosina (APNEA), N6-(4- amino-3-yodobencil)adenosina-5'-(N-metiluronamida) (AB-MECA), N6-(3-yodobencil)-adenosina-5'-Nmetiluronamida (IB-MECA) y 2-cloro-N6-(3-yodobencil)-adenosina-5'-N-metiluronamida (CI-IB-MECA).

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients
70	Carbohydrates; Sugars; Derivatives thereof
7042	Compounds having saccharide radicals and heterocyclic rings
7052	having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
706	containing six-membered rings with nitrogen as a ring hetero atom
7064	containing condensed or non-condensed pyrimidines
7076	containing purines, e.g. adenosine, adenylic acid

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
P	SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1	Drugs for disorders of the alimentary tract or the digestive system
16	for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9	Medicinal preparations characterised by special physical form

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients
70	Carbohydrates; Sugars; Derivatives thereof
7042	Compounds having saccharide radicals and heterocyclic rings
7052	having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
706	containing six-membered rings with nitrogen as a ring hetero atom
7064	containing condensed or non-condensed pyrimidines
7076	containing purines, e.g. adenosine, adenylic acid

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
P	SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1	Drugs for disorders of the alimentary tract or the digestive system
16	for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

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1. ES2848150 - Un ligando del receptor de adenosina A3 para su uso en el tratamiento de la acumulación de grasa ectópica