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1. ES2357832 - GENES SENSIBLES A CRH EN EL CNS.

Office
Spain
Application Number 03758054
Application Date 23.10.2003
Publication Number 2357832
Publication Date 03.05.2011
Publication Kind T3
IPC
C12Q 1/68
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
C07K 14/575
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
575Hormones
CPC
A61P 25/24
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
24Antidepressants
C07K 14/47
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
46from vertebrates
47from mammals
C12Q 1/6883
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms
68involving nucleic acids
6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
6883for diseases caused by alterations of genetic material
C12Q 2600/158
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
2600Oligonucleotides characterized by their use
158Expression markers
Applicants JANSSEN PHARMACEUTICA N.V.
Inventors PEETERS, Pieter Johan,Janssen Pharmaceutica N.V.
GÖHLMANN, Hinrich W.H.,Janssen Pharmaceutica N.V.
SWAGEMAKERS, Sigrid, Maria, Alice
KASS, Stefan Ulrich,Janssen Pharmaceutica N.V.
STECKLER, Thomas H.W.Janssen Pharmaceutica N.V.
FIERENS, Frederik, L.P.Janssen Pharmaceutica N.V.
Agents DE JUSTO DE JUSTO MARIO
Priority Data 0212274 31.10.2002 EP
Title
(ES) GENES SENSIBLES A CRH EN EL CNS.
Abstract
(ES)
Un método para identificar un compuesto capaz de alterar la respuesta de exposición prolongada de CRH en una célula, comprendiendo dicho método: a) poner en contacto dicha célula con CRH en presencia y ausencia de dicho compuesto; b) determinar la cantidad de al menos una proteína que modula la señalización de la hormona liberadora de corticotropina (CRH) en dicha célula; y c) comparar la cantidad de dicha proteína en presencia y ausencia de dicho compuesto; en el cual la proteína que modula la señalización de la hormona liberadora de corticotropina (CRH) es SEQ ID NO. 20.