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1. EP2654842 - AUTO-INJECTOR

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Office
European Patent Office
Application Number 11804559
Application Date 21.12.2011
Publication Number 2654842
Publication Date 30.10.2013
Publication Kind B1
IPC
A61M 5/315
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
5Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
178Syringes
31Details
315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod; Appliances on the rod for facilitating dosing
A61M 5/20
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
5Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
178Syringes
20Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
A61M 5/32
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
5Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
178Syringes
31Details
32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
CPC
A61M 5/2033
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
5Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
178Syringes
20Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
2033Spring-loaded one-shot injectors with or without automatic needle insertion
A61M 5/31583
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
5Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
178Syringes
31Details
315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod ; or piston; Appliances on the rod for facilitating dosing ; ; Dosing mechanisms
31565Administration mechanisms, i.e. constructional features, modes of administering a dose
31576Constructional features or modes of drive mechanisms for piston rods
31583based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
A61M 5/326
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
5Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
178Syringes
31Details
32Needles; Details of needles pertaining to their connection with syringe or hub
3205Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
321Means for protection against accidental injuries by used needles
3243being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
326Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
A61M 2005/206
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
5Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
178Syringes
20Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
206With automatic needle insertion
A61M 2005/208
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
5Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
178Syringes
20Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
2073preventing premature release, e.g. by making use of a safety lock
208Release is possible only when device is pushed against the skin, e.g. using a trigger which is blocked or inactive when the device is not pushed against the skin
A61M 5/3204
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
5Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
178Syringes
31Details
32Needles; Details of needles pertaining to their connection with syringe or hub
3202Devices for protection of the needle before use, e.g. caps
3204Needle cap remover, i.e. devices to dislodge protection cover from needle or needle hub, e.g. deshielding devices
Applicants SANOFI AVENTIS DEUTSCHLAND
Inventors KEMP THOMAS MARK
BARROW-WILLIAMS TIMOTHY DONALD
EKMAN MATTHEW
Designated States
Priority Data 10196073 21.12.2010 EP
11804559 21.12.2011 EP
201161432241 13.01.2011 US
Title
(DE) AUTOMATISCHER INJEKTOR
(EN) AUTO-INJECTOR
(FR) INJECTEUR AUTOMATIQUE
front page image
Abstract
(EN) The invention refers to an auto-injector (1) for administering a dose of a liquid medicament (M), comprising: - an elongate housing (2) arranged to contain a syringe (7) with a hollow needle (19) and a stopper (10) for sealing the syringe (7) and displacing the medicament (M), the elongate housing (2) having a distal end (D) and a proximal end (P) with an orifice intended to be applied against an injection site, wherein the syringe (7) is slidably arranged with respect to the housing (2), - spring means (14) capable of, upon activation, pushing the needle (9) from a covered position inside the housing (2) into an advanced position through the orifice and past the proximal end (P), operating the syringe (7) to supply the dose of medicament (M), and covering the needle (19) on removal of the auto-injector (1) from the injection site, - activating means (4, 20, 24) arranged to lock the spring means (14) in a pressurized state prior to manual operation and capable of, upon manual operation, releasing the spring means (14) for injection, characterized in that the spring means (14) is a torsion spring (14), wherein a first gear arrangement (13, 13.1, 9) and a second gear arrangement (15, 11.1, 11) are arranged for respectively converting torque from a first end (14.1) and a second end (14.2) of the torsion spring (14) into a translative force, wherein the first end (14.1) is arranged to be groundable in the housing (2) while the second end (14.2) is configured to act on a plunger (11) through the second gear arrangement (15, 11.1, 11) for advancing the needle (19) and supplying the dose, wherein the activating means (4, 20, 24) is arranged to block or release the second gear arrangement (15, 11.1, 11) and wherein the first end (14.1) is releasable from the ground in the housing (2) for causing a translation through the first gear arrangement (13, 13.1, 9) resulting in the needle (19) getting covered.
(FR) L'invention concerne un injecteur automatique (1) qui permet d'administrer une dose d'un médicament liquide (M) et qui comporte : - un boîtier allongé (2) agencé pour contenir une seringue (7) ayant une aiguille creuse (19) et un bouchon (10) pour sceller de manière étanche la seringue (7) et pour déplacer le médicament (M), le boîtier allongé (2) ayant une extrémité distale (D) et une extrémité proximale (P) ayant un orifice destiné à être appliqué contre un site d'injection, la seringue (7) étant agencée de manière coulissante par rapport au boîtier (2), - un moyen de ressort (14) pouvant, lors d'une activation, pousser l'aiguille (9) d'une position recouverte, à l'intérieur du boîtier (2), vers une position avancée à travers l'orifice et devant l'extrémité proximale (P), actionner la seringue (7) pour fournir la dose de médicament (M) et recouvrir l'aiguille (19), lorsque l'injecteur automatique (1) est retiré du site d'injection, - des moyens d'activation (4, 20, 24) agencés pour verrouiller le moyen de ressort (14) dans un état sous pression, avant un fonctionnement manuel, et pouvant, lors d'un actionnement manuel, libérer le moyen de ressort (14) pour une injection, et caractérisés en ce que le moyen de ressort (14) est un ressort de torsion (14), un premier agencement d'engrenage (13, 13.1, 9) et un second agencement d'engrenage (15, 11.1, 11) étant agencés pour convertir respectivement un couple issu d'une première extrémité (14.1) et d'une seconde extrémité (14.2) du ressort de torsion (14) en une force de translation, la première extrémité (14.1) étant conçue pour être mise à la masse dans le boîtier (2), alors que la seconde extrémité (14.2) est configurée pour agir sur un piston (11) par l'intermédiaire du second agencement d'engrenage (15, 11.1, 11) pour faire avancer l'aiguille (19) et pour fournir la dose, les moyens d'activation (4, 20, 24) étant agencés pour bloquer ou libérer le second agencement d'engrenage (15, 11.1, 11), la première extrémité (14.1) pouvant être libérée de la masse dans le boîtier (2) pour provoquer une translation à travers le premier agencement d'engrenage (13, 13.1, 9) conduisant à la couverture de l'aiguille (19).
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