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1. EP2635895 - MEASUREMENT SYSTEM FOR FLUORESCENT DETECTION, AND METHOD THEREFOR

Office European Patent Office
Application Number 10782409
Application Date 03.11.2010
Publication Number 2635895
Publication Date 11.09.2013
Publication Kind A1
IPC
G01N 21/64
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
63optically excited
64Fluorescence; Phosphorescence
G02B 21/00
GPHYSICS
02OPTICS
BOPTICAL ELEMENTS, SYSTEMS, OR APPARATUS
21Microscopes
CPC
G01N 21/6428
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
63optically excited
64Fluorescence; Phosphorescence
6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
G01N 21/6452
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
63optically excited
64Fluorescence; Phosphorescence
645Specially adapted constructive features of fluorimeters
6452Individual samples arranged in a regular 2D-array, e.g. multiwell plates
Applicants REAMETRIX INC
Inventors MANIAN BALA S
Designated States
Priority Data 2010054967 03.11.2010 IB
Title
(DE) MESSSYSTEM ZUR FLUORESZENZDETEKION UND VERFAHREN DAFÜR
(EN) MEASUREMENT SYSTEM FOR FLUORESCENT DETECTION, AND METHOD THEREFOR
(FR) SYSTÈME DE MESURE POUR LA DÉTECTION DE FLUORESCENCE, ET PROCÉDÉ ASSOCIÉ
Abstract
(EN)
In one aspect, the invention provides a measurement system, wherein the measurement system comprises a sample module (10) to receive a sample, wherein the sample module comprises at least one fluorophore; an optics module (20) to generate an incident beam to impinge on the sample to yield a laser spot; a detector module (30) to detect fluorescence signals arising out of the sample.; a processor module (40) to process the fluorescence signals and provide relevant output; an output module (50); a control module (60) to control the sample module, the optics module (20), the detector module (30) and the output module (50). The measurement system of the invention is capable of measuring both bulk and event fluorescences of a sample containing at least one fluorophore. In another aspect, the invention provides a method for testing a fluid based on the measurement system of the invention.

(FR)
Selon l'un de ses aspects, l'invention concerne un système de mesure comprenant un module à échantillon (10) destiné à recevoir un échantillon, le module à échantillon comprenant au moins un fluorophore ; un module optique (20) destiné à générer un faisceau incident projeté sur l'échantillon pour produire un point laser ; un module détecteur (30) destiné à détecter des signaux de fluorescence provenant de l'échantillon ; un module de traitement (40) destiné à traiter les signaux de fluorescence et à fournir une sortie pertinente ; un module de sortie (50) ; un module de commande (60) destiné à commander le module à échantillon, le module optique (20), le module détecteur (30) et le module de sortie (50). Le système de mesure de l'invention est capable de mesurer à la fois des fluorescences globales et événement par événement d'un échantillon contenant au moins un fluorophore. Selon un autre aspect, l'invention concerne un procédé permettant de tester un fluide sur la base du système de mesure de l'invention.

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