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1. EP2632550 - METHODS AND COMPOSITIONS FOR TREATING HIV-ASSOCIATED DIARRHEA

Office European Patent Office
Application Number 11837249
Application Date 31.10.2011
Publication Number 2632550
Publication Date 04.09.2013
Publication Kind B1
IPC
A61P 1/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
12Antidiarrhoeals
CPC
A61K 31/05
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
05Phenols
A61K 31/353
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
335having oxygen as the only ring hetero atom, e.g. fungichromin
35having six-membered rings with one oxygen as the only ring hetero atom
352condensed with carbocyclic rings, e.g. cannabinols, methantheline
3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
A61P 1/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
A61P 1/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
12Antidiarrhoeals
A61P 25/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
04Centrally acting analgesics, e.g. opioids
A61P 31/18
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
14for RNA viruses
18for HIV
Applicants NAPO PHARMACEUTICALS INC
Inventors FORBES WILLIAM
BORTEY ENOCH
KING STEVEN
CHATURVEDI PRAVIN
Designated States
Priority Data 2011058549 31.10.2011 US
201161434379 19.01.2011 US
40862210 31.10.2010 US
40933510 02.11.2010 US
41624910 22.11.2010 US
Title
(DE) VERFAHREN UND ZUSAMMENSETZUNGEN ZUR BEHANDLUNG VON HIV-ASSOZIIERTER DIARRHOE
(EN) METHODS AND COMPOSITIONS FOR TREATING HIV-ASSOCIATED DIARRHEA
(FR) PROCÉDÉS ET COMPOSITIONS POUR LE TRAITEMENT DE LA DIARRHÉE ASSOCIÉE AU HIV
Abstract
(EN)
Presented herein are methods for treating diarrhea by administering to a patient in need thereof, an inhibitor of chloride-ion transport in an amount sufficient to treat diarrhea. Treatment of diarrhea includes the treatment of the diarrhea as well as the pain, abdominal discomfort and other symptoms associated with diarrhea. In one embodiment, the inhibitor of chloride-ion transport is crofelemer.

(FR)
L'invention concerne des procédés pour le traitement de la diarrhée par administration à un patient ayant besoin d'un tel traitement, d'un inhibiteur du transport d'ions chlorure dans une quantité suffisante pour le traitement de la diarrhée. Le traitement de la diarrhée comporte le traitement de la diarrhée ainsi que le traitement de la douleur, de la gêne abdominale et d'autres symptômes associés à la diarrhée. Dans un mode de réalisation, l'inhibiteur du transport d'ions chlorure est le crofelemer.