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1. EP2583676 - Oleocanthal for treating pain

Office European Patent Office
Application Number 13152065
Application Date 09.05.2006
Publication Number 2583676
Publication Date 24.04.2013
Publication Kind A1
IPC
A61K 31/222
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
21Esters, e.g. nitroglycerine, selenocyanates
215of carboxylic acids
22of acyclic acids, e.g. pravastatin
222with compounds having aromatic groups, e.g. dipivefrine, ibopamine
A61P 29/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
29Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents; Non-steroidal antiinflammatory drugs (NSAIDs)
CPC
C07C 67/56
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
67Preparation of carboxylic acid esters
48Separation; Purification; Stabilisation; Use of additives
56by solid-liquid treatment; by chemisorption
A61K 31/222
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
21Esters, e.g. nitroglycerine, selenocyanates
215of carboxylic acids
22of acyclic acids, e.g. pravastatin
222with compounds having aromatic groups, e.g. dipivefrine, ibopamine
C07C 67/313
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
67Preparation of carboxylic acid esters
30by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
313by introduction of doubly bound oxygen containing functional groups, e.g. carboxyl groups
C07C 67/58
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
67Preparation of carboxylic acid esters
48Separation; Purification; Stabilisation; Use of additives
58by liquid-liquid treatment
Applicants UNIV PENNSYLVANIA
MONELL CHEMICAL SENSES CENTRE
Inventors KEAST RUSSELL S J
HAN QIANG
SMITH AMOS B III
BEAUCHAMP GARY K
BRESLIN PAUL A S
LIN JIANMING
Priority Data 06759410 09.05.2006 EP
67913605 09.05.2005 US
70356505 29.07.2005 US
Title
(DE) Oleocanthal zur Behandlung von Schmerzen
(EN) Oleocanthal for treating pain
(FR) Oléocanthal pour traiter la douleur
Abstract
(EN)
The invention provides methods of synthesizing the purified enantiomers of oleocanthal. The invention further provides oleocanthals in various formulations for use in a method of treating pain.