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1. EP2425874 - Use of a vitamin D compound and an additional therapeutic agent for the treatment of cancer

Office European Patent Office
Application Number 11175046
Application Date 23.08.2007
Publication Number 2425874
Publication Date 07.03.2012
Publication Kind A3
IPC
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
56
Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
57
substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane, progesterone
573
substituted in position 21, e.g. cortisone, dexamethasone, prednisone
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
59
Compounds containing 9,10-seco-cyclopenta[a]hydro- phenanthrene ring systems
592
9,10-Secoergostane derivatives, e.g. ergocalciferol, vitamin D2
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
59
Compounds containing 9,10-seco-cyclopenta[a]hydro- phenanthrene ring systems
593
9,10-Secocholestane derivatives, e.g. cholecalciferol, vitamin D3
A61P 35/00
A61K 31/573
A61K 31/592
A61K 31/593
CPC
A61K 45/06
A61K 31/337
A61K 31/573
A61K 31/59
A61K 31/593
Applicants COUGAR BIOTECHNOLOGY INC
Inventors AUERBACH ALAN H
BELLDEGRUN ARIE S
Designated States
Priority Data 07837327 23.08.2007 EP
93492406 25.08.2006 US
Title
(DE) Verwendung von einer Vitamin D Verbindung und eines zusätzlichen therapeutischen Mittel in der Behandlung von Krebs
(EN) Use of a vitamin D compound and an additional therapeutic agent for the treatment of cancer
(FR) Utilisation de la vitamine D et un agent thérapeutique supplémentaire pour le traitment du cancer
Abstract
(EN)
Methods and compositions for treating cancer are described herein. More particularly, the methods for treating cancer comprise administering a vitamin D compound in combination with at least one additional therapeutic agent, such as an anti-cancer agent or a steroid. Furthermore, disclosed are compositions comprising vitamin D compounds and at least one additional therapeutic agent, such as an anti-cancer agent or a steroid, e.g., corticosteroid or more specifically, a glucocorticoid.

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