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1. EP3965727 - MICROPARTICLES COMPRISING CELLULOSE NANOCRYSTALS AGGREGATED WITH PROTEINS AND COSMETIC USES THEREOF

Office
European Patent Office
Application Number 20805172
Application Date 06.05.2020
Publication Number 3965727
Publication Date 16.03.2022
Publication Kind A1
IPC
A61K 8/73
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
72containing organic macromolecular compounds
73Polysaccharides
A61K 8/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
02characterised by special physical form
A61K 8/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
02characterised by special physical form
04Dispersions; Emulsions
A61K 8/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
02characterised by special physical form
04Dispersions; Emulsions
06Emulsions
A61K 8/64
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
64Proteins; Peptides; Derivatives or degradation products thereof
A61K 9/14
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
14Particulate form, e.g. powders
CPC
A61K 8/64
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
64Proteins; Peptides; Derivatives or degradation products thereof
C07K 17/12
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
17Carrier-bound or immobilised peptides
02Peptides being immobilised on, or in, an organic carrier
10the carrier being a carbohydrate
12Cellulose or derivatives thereof
A61K 8/731
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
72containing organic macromolecular compounds
73Polysaccharides
731Cellulose; Quaternized cellulose derivatives
A61K 2800/412
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
2800Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
40Chemical, physico-chemical or functional or structural properties of particular ingredients
41Particular ingredients further characterized by their size
412Microsized, i.e. having sizes between 0.1 and 100 microns
A61K 2800/413
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
2800Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
40Chemical, physico-chemical or functional or structural properties of particular ingredients
41Particular ingredients further characterized by their size
413Nanosized, i.e. having sizes below 100 nm
A61K 8/0287
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
02characterised by special physical form
0241Containing particulates characterized by their shape and/or structure
0283Matrix particles
0287the particulate containing a solid-in-solid dispersion
Applicants ANOMERA INC
Inventors ANDREWS MARK P
MORSE TIMOTHY
RAK MONIKA
WU JUNQI
HU ZHEN
BATEMAN MARY
Designated States
Priority Data 201962846281 10.05.2019 US
Title
(DE) MIKROPARTIKEL MIT CELLULOSE-NANOKRISTALLEN, DIE MIT PROTEINEN AGGREGIERT SIND, UND DEREN KOSMETISCHE VERWENDUNGEN
(EN) MICROPARTICLES COMPRISING CELLULOSE NANOCRYSTALS AGGREGATED WITH PROTEINS AND COSMETIC USES THEREOF
(FR) MICROPARTICULES COMPORTANT DES NANOCRISTAUX DE CELLULOSE AGRÉGÉS AVEC DES PROTÉINES ET LEURS UTILISATIONS COSMÉTIQUES
Abstract
(EN) Proteinaceous cellulose microparticles are provided. These microparticles comprise cellulose nanocrystals and one or more peptide, one or more protein, or a mixture thereof, wherein the nanocrystals and the peptide(s) and/or protein(s) are aggregated together to form the microparticles. In embodiments, the microparticles comprise silk fibroin and advantageously are hydrophobic and lipophilic. There are also provided cosmetic preparations comprising these microparticles. In advantageous embodiments, these cosmetic preparations comprise a water-in-oil emulsion or a lipophilic medium. Finally, there are also provided methods of producing the microparticles.
(FR) L'invention concerne des microparticules de cellulose à base de protéines. Ces microparticules comportent des nanocristaux de cellulose et un ou plusieurs peptides, une ou plusieurs protéines, ou un mélange de ceux-ci, les nanocristaux et le ou les peptides et/ou la ou les protéines étant agrégés pour former les microparticules. Dans des modes de réalisation, les microparticules comportent de la fibroïne de soie, et, ce qui est un avantage, sont hydrophobes et lipophiles. L'invention concerne également des préparations cosmétiques comportant ces microparticules. Dans des modes de réalisation qui présentent des avantages, ces préparations cosmétiques comportent une émulsion eau dans huile ou un milieu lipophile. Enfin, l'invention concerne également des procédés de fabrication de ces microparticules.