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1. EP3902925 - METHOD FOR MEASURING TELOMERE ASSOCIATED VARIABLES AND USES THEREOF FOR THE DIAGNOSIS AND/OR PROGNOSIS OF TELOMERIC-ASSOCIATED DISEASES

Office
European Patent Office
Application Number 19831757
Application Date 24.12.2019
Publication Number 3902925
Publication Date 03.11.2021
Publication Kind A1
IPC
C12Q 1/6841
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
6813Hybridisation assays
6841In situ hybridisation
G16B 5/00
GPHYSICS
16INFORMATION AND COMMUNICATION TECHNOLOGY SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
5ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
CPC
C12Q 1/6841
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms
68involving nucleic acids
6813Hybridisation assays
6841In situ hybridisation
Applicants LIFE LENGTH S L
Inventors NAJARRO PARRA MARÍA PILAR
FERNÁNDEZ CANIVELL LUIS
ESTEBAN LA FUENTE LAURA
DE PEDRO MONTEJO NURIA
DIEZ ZAERA MARÍA
GARCIA MARTÍNEZ JORGE
Designated States
Priority Data 18382992 26.12.2018 EP
Title
(DE) VERFAHREN ZUR MESSUNG VON TELOMERASSOZIIERTEN VARIABLEN UND VERWENDUNGEN DAVON ZUR DIAGNOSE UND/ODER PROGNOSE VON TELOMERASSOZIIERTEN ERKRANKUNGEN
(EN) METHOD FOR MEASURING TELOMERE ASSOCIATED VARIABLES AND USES THEREOF FOR THE DIAGNOSIS AND/OR PROGNOSIS OF TELOMERIC-ASSOCIATED DISEASES
(FR) PROCÉDÉ DE MESURE DE VARIABLES ASSOCIÉES AU TÉLOMÈRES ET LEURS UTILISATIONS POUR LE DIAGNOSTIC ET/OU LE PRONOSTIC DE MALADIES ASSOCIÉES AU TÉLOMÈRES
Abstract
(EN) The invention provided methods in vitro for diagnosis and/or prognosis of a clinical outcome in a subject with a telomere-associated disease comprising determining specific telomere associated variables (TAVs) of a test sample cell from the subject, wherein the value of the TAVs obtained for the test sample compared to a control sample is indicative of the telomerase-associated disease and/or the clinical outcome of the subject.
(FR) L'invention concerne des procédés in vitro pour le diagnostic et/ou le pronostic d'un résultat clinique chez un sujet atteint d'une maladie associée aux télomères, comprenant la détermination de variables associées à des télomères spécifiques (TAV) d'une cellule d'échantillon à analyser prélevée chez le sujet, la valeur des TAV obtenues pour l'échantillon à analyser par comparaison avec un échantillon témoin indiquant la maladie associée à la télomérase et/ou le résultat clinique du sujet.
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