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1. EP3880666 - COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY

Office
European Patent Office
Application Number 19821320
Application Date 11.11.2019
Publication Number 3880666
Publication Date 22.09.2021
Publication Kind A1
IPC
C07D 275/06
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
275Heterocyclic compounds containing 1, 2-thiazole or hydrogenated 1,2-thiazole rings
04condensed with carbocyclic rings or ring systems
06with hetero atoms directly attached to the ring sulfur atom
A61K 31/4245
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
41having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
4245Oxadiazoles
A61P 35/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
C07D 417/12
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
417Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/196
02containing two hetero rings
12linked by a chain containing hetero atoms as chain links
CPC
C07D 275/06
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
275Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
04condensed with carbocyclic rings or ring systems
06with hetero atoms directly attached to the ring sulfur atom
C07D 417/12
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
417Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
02containing two hetero rings
12linked by a chain containing hetero atoms as chain links
A61P 35/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
Applicants NOVARTIS AG
Inventors KATZ JASON
ROUSH WILLIAM
SEIDEL HANS MARTIN
SHEN DONG-MING
VENKATRAMAN SHANKAR
Designated States
Priority Data 201862760244 13.11.2018 US
201862760248 13.11.2018 US
201862760279 13.11.2018 US
201962795373 22.01.2019 US
201962796356 24.01.2019 US
201962796361 24.01.2019 US
Title
(DE) VERBINDUNGEN UND ZUSAMMENSETZUNGEN ZUR BEHANDLUNG VON ERKRANKUNGEN IN ZUSAMMENHANG MIT NLRP-AKTIVITÄT
(EN) COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY
(FR) COMPOSÉS ET COMPOSITIONS DESTINÉS AU TRAITEMENT D'ÉTATS PATHOLOGIQUES ASSOCIÉS À UNE ACTIVITÉ NLRP
Abstract
(EN) In one aspect, compounds of Formula AA, or a pharmaceutically acceptable salt thereof, are featured or a pharmaceutically acceptable salt thereof, wherein the variables shown in Formula A can be as defined anywhere herein.
(FR) Selon un aspect, l'invention concerne des composés représentés par la formule AA, ou un sel pharmaceutiquement acceptable de ceux-ci, ou un sel pharmaceutiquement acceptable de ceux-ci, les variables indiquées dans la formule A pouvant être telles que définies dans la description.
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