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1. (EP2389227) METHODS FOR TREATING ACUTE MYOCARDIAL INFARCTIONS AND ASSOCIATED DISORDERS

Office : European Patent Office
Application Number: 10734007 Application Date: 26.01.2010
Publication Number: 2389227 Publication Date: 30.11.2011
Publication Kind : A4
Designated States: AL, AT, BA, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR
Prior PCT appl.: Application Number:US2010022112 ; Publication Number: Click to see the data
IPC:
A61P 9/10
A61K 31/4412
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9
Drugs for disorders of the cardiovascular system
10
for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
44
Non-condensed pyridines; Hydrogenated derivatives thereof
4412
having oxo groups directly attached to the heterocyclic ring
CPC:
A61K 31/415
A61K 31/00
A61K 31/4365
A61K 31/437
A61K 31/4418
A61K 31/4433
A61K 31/4436
A61K 31/4439
A61K 31/444
A61K 31/496
A61K 31/4965
A61K 31/50
A61K 31/506
A61K 31/513
A61K 31/53
A61K 31/5377
A61K 31/706
Applicants: INTERMUNE INC
UNIV CALIFORNIA
Inventors: OLGIN JEFF
KOSSEN KARL
Priority Data: 14734009 26.01.2009 US
2010022112 26.01.2010 US
Title: (DE) VERFAHREN ZUR BEHANDLUNG VON AKUTEN MYOKARDINFARKTEN UND DAMIT ASSOZIIERTEN ERKRANKUNGEN
(EN) METHODS FOR TREATING ACUTE MYOCARDIAL INFARCTIONS AND ASSOCIATED DISORDERS
(FR) MÉTHODES DE TRAITEMENT D'INFARCTUS DU MYOCARDE AIGUS ET TROUBLES ASSOCIÉS
Abstract:
(EN) The invention relates to methods of treating patients who have suffered an acute myocardial infarction (AMI) with a therapeutic that has anti-fibrotic effects, for example, pirfenidone and analogs thereof The method of treating a patient who has suffered an acute myocardial infarction may include administering to the patient a therapeutically effective dose of a therapeutic having an anti-fibrotic effect, wherein optionally the treatment is initiated at a time period about 1 to 42 days after suffering the AMI, and optionally continues for up to 3 to 6 months
(FR) L'invention concerne des méthodes de traitement de patients qui ont souffert d'un infarctus du myocarde aigu (AMI) avec un agent thérapeutique qui possède des effets anti-fibreux, par exemple, la pirfénidone et ses analogues. La méthode de traitement d'un patient qui a souffert d'un infarctus du myocarde aigu peut comprendre l'administration au patient d'une dose efficace d'un point de vue thérapeutique d'un agent thérapeutique possédant un effet anti-fibreux, le traitement étant facultativement commencé environ 1 à 42 jours après l'occurrence de l'AMI, et continuant facultativement pendant 3 à 6 mois.
Also published as:
NZ593583UAa201109441IL213526MXMX/a/2011/007854SG172981JP2012515800
CN102292124CA2747251MX2011007854KR1020110114684TN2011000364BRPI1006979
AU2010206543ID2012/00475MYPI 2011003334IN5985/DELNP/2011WO/2010/085805