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1. EP2385841 - PREVENTION AND/OR TREATMENT OF MULTIPLE ORGAN DYSFUNCTION SYNDROME WITH INTERLEUKIN-22

Office European Patent Office
Application Number 10729641
Application Date 11.01.2010
Publication Number 2385841
Publication Date 16.11.2011
Publication Kind B1
IPC
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
19
Cytokines; Lymphokines; Interferons
20
Interleukins
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43
Drugs for specific purposes, not provided for in groups A61P1/-A61P41/108
A61K 38/20
A61P 43/00
CPC
A61K 38/20
A61K 38/2066
Applicants GENERON SHANGHAI CORP
Inventors HUANG YU LIANG
HUANG ZHI HUA
SUN QI
Designated States
Priority Data 14413409 12.01.2009 US
2010020673 11.01.2010 US
Title
(DE) PRÄVENTION UND/ODER BEHANDLUNG VON MULTIPLEM ORGANVERSAGEN MIT INTERLEUKIN-22
(EN) PREVENTION AND/OR TREATMENT OF MULTIPLE ORGAN DYSFUNCTION SYNDROME WITH INTERLEUKIN-22
(FR) PRÉVENTION ET/OU TRAITEMENT DU SYNDROME DE DÉFAILLANCE MULTIVISCÉRALE AVEC DE L'INTERLEUKINE 22
Abstract
(EN)
The present invention relates to use an agent for the prevention and/or treatment of multiple organ dysfunction syndrome (MODS) or multiple organ failure (MOF) comprising interleukin-22 (IL-22) as an effective ingredient. The present invention is applicable to prevention of or therapy for diseases from sepsis, septic shock, liver failure, to multiple organ dysfunction syndromes. More particularly, the present invention is useful for an emergency medical service, for treatment of injury caused by a traffic accident, burns, heat attacks, hypercytokinemia or severe infective diseases.

(FR)
La présente invention concerne l'utilisation d'un agent pour la prévention et/ou le traitement du syndrome de défaillance multiviscérale ou d'une insuffisance polyviscérale, comprenant de l'interleukine 22 (IL‑22) en tant que principe actif. La présente invention s'applique à la prévention ou au traitement de maladies de la septicémie, du choc septique, de l'insuffisance hépatique aux syndromes de défaillance multiviscérale. De manière plus particulière, la présente invention est utile pour un service médical d'urgence, pour le traitement des lésions provoquées par un accident de la circulation, des brûlures, des crises cardiaques, d'une hypercytokinémie ou de maladies infectieuses sévères.