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1. (EP2381966) PDGF-R BINDERS

Office : European Patent Office
Application Number: 09795979 Application Date: 17.12.2009
Publication Number: 2381966 Publication Date: 02.11.2011
Publication Kind : A2
Designated States: AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR
Prior PCT appl.: Application Number:EP2009067447 ; Publication Number: Click to see the data
IPC:
A61K 49/14
A61K 51/08
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
49
Preparations for testing in vivo
06
Nuclear magnetic resonance (NMR) contrast preparations; Magnetic resonance imaging (MRI) contrast preparations
08
characterised by the carrier
10
Organic compounds
14
Peptides, e.g. proteins
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
51
Preparations containing radioactive substances for use in therapy or testing in vivo
02
characterised by the carrier
04
Organic compounds
08
Peptides, e.g. proteins
CPC:
A61K 51/088
A61K 49/085
A61K 49/14
A61K 51/08
A61K 51/1027
C07K 2319/00
Applicants: GEN ELECTRIC
Inventors: MARINO MICHAEL ERNEST
SYUD FAISAL AHMED
SCHAFFER PAUL
LEE BRIAN DUH-LAN
ZHANG RONG
LINDBORG MALIN
GUNNERIUSSON ELIN
LENDEL CHRISTOFER
Priority Data: 336780 null
EP2009067447 null
US20080336780 null
WO2009EP67447 null
2009067447 17.12.2009 EP
33678008 17.12.2008 US
Title: (DE) PDGF-R-BINDER
(EN) PDGF-R BINDERS
(FR) AGENTS SE LIANT AU PDGF-R
Abstract:
(EN) Provided herein are PDGF-Rβ imaging agents that are polypeptides labeled with a signal generator (e.g., paramagnetic label, a radionuclide, or a fluorophore), wherein the imaging agents bind specifically to PDGFR-β. Also provided are in vivo imaging methods using the imaging agents.
(FR) Cette invention concerne des agents d'imagerie PDGF-Rβ qui sont des polypeptides marqués avec un générateur de signal (par exemple marqueur paramagnétique, isotope ou fluorophore), lesdits agents d'imagerie se liant spécifiquement au PDGF-Rβ. L'invention décrit également des procédés d'imagerie in vivo utilisant lesdits agents d'imagerie.
Also published as:
JP2012512233CN102316903WO/2010/079079