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1. EP3411330 - CARBON DOTS FOR DIAGNOSTIC ANALYSIS AND DRUG DELIVERY

Office European Patent Office
Application Number 17748361
Application Date 06.02.2017
Publication Number 3411330
Publication Date 12.12.2018
Publication Kind A4
IPC
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
48
Preparations in capsules, e.g. of gelatin, of chocolate
50
Microcapsules
51
Nanocapsules
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
06
Organic compounds
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
49
Preparations for testing in vivo
B PERFORMING OPERATIONS; TRANSPORTING
82
NANO-TECHNOLOGY
Y
SPECIFIC USES OR APPLICATIONS OF NANO-STRUCTURES; MEASUREMENT OR ANALYSIS OF NANO-STRUCTURES; MANUFACTURE  OR TREATMENT OF NANO-STRUCTURES
5
Nano-biotechnology or nano-medicine, e.g. protein engineering or drug delivery
[IPC code unknown for C01B 32/15]
A61K 9/51
A61K 47/06
A61K 49/00
B82Y 5/00
C01B 32/15
CPC
A61K 9/0019
A61K 9/5123
A61K 47/06
A61K 49/0065
B82Y 5/00
C01B 32/15
Applicants UNIV MIAMI
Inventors LI SHANGHAO
LEBLANC ROGER M
SKROMNE ISAAC
PENG ZHILI
Designated States
Priority Data 201662292026 05.02.2016 US
2017016743 06.02.2017 US
Title
(DE) KOHLENSTOFFQUANTENPUNKTE ZUR DIAGNOSTISCHEN ANALYSE UND WIRKSTOFFFREISETZUNG
(EN) CARBON DOTS FOR DIAGNOSTIC ANALYSIS AND DRUG DELIVERY
(FR) POINTS DE CARBONE POUR UNE ANALYSE DIAGNOSTIQUE ET L'ADMINISTRATION DE MÉDICAMENTS
Abstract
(EN)
The disclosure provides a method of forming carbon dots, including admixing carbon powder with sulfuric acid and nitric acid and heating the carbon powder mixture to reflux to oxidize the carbon powder. The method further includes isolating and purifying the carbon dots. The disclosure further provides applications of the carbon dots for diagnostic analysis (such as bone analysis), fibrillation inhibition, and drug delivery.

(FR)
L'invention concerne un procédé de formation de points de carbone, consistant à mélanger une poudre de carbone avec de l'acide sulfurique et de l'acide nitrique et à chauffer le mélange de poudre de carbone à reflux pour oxyder la poudre de carbone. Le procédé consiste en outre à isoler et à purifier les points de carbone. L'invention concerne en outre des applications des points de carbone pour une analyse diagnostique (telle qu'une analyse osseuse), l'inhibition d'une fibrillation, et l'administration de médicaments.