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1. (EP3411069) HUMANIZED ANTI-CD3 ANTIBODIES, CONJUGATES AND USES THEREOF

Office : European Patent Office
Application Number: 17748229 Application Date: 03.02.2017
Publication Number: 3411069 Publication Date: 12.12.2018
Publication Kind : A2
Designated States: AL, AT, BA, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, ME, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR
Prior PCT appl.: Application Number:US2017016407 ; Publication Number: Click to see the data
IPC:
A61K 39/395
C07K 16/28
C07K 16/46
C07K 19/00
C12N 15/13
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
28
against receptors, cell surface antigens or cell surface determinants
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
46
Hybrid immunoglobulins
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
19
Hybrid peptides
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
11
DNA or RNA fragments; Modified forms thereof
12
Genes encoding animal proteins
13
Immunoglobulins
CPC:
C07K 16/2803
A61K 47/6803
A61K 47/6849
A61K 47/6869
C07K 2317/24
C07K 2317/33
C07K 2317/56
C07K 2317/73
C07K 2317/77
C07K 2317/92
Applicants: THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RES
Inventors: KIM CHANHYUK
YOUNG TRAVIS
KIM MINSOO
MA JENNIFER
PRESTA LEONARD
SCHULTZ PETER G
Priority Data: 201662291143 04.02.2016 US
2017016407 03.02.2017 US
Title: (DE) HUMANISIERTE ANTI-CD3-ANTIKÖRPER, KONJUGATE UND VERWENDUNGEN DAFÜR
(EN) HUMANIZED ANTI-CD3 ANTIBODIES, CONJUGATES AND USES THEREOF
(FR) ANTICORPS HUMANISÉS ANTI-CD3, CONJUGUÉS ET LEURS UTILISATIONS
Abstract:
(EN) The present invention provides for humanized anti-CD3 antibodies and conjugates thereof. These conjugates may be useful in the treatment of conditions such as prostate cancer.
(FR) La présente invention concerne des anticorps anti-CD3 humanisés et leurs conjugués. Ces conjugués peuvent être utiles dans le traitement d'affections telles que le cancer de la prostate.
Also published as:
AU2017213886CA3013463KR1020180104157CN109069635WO/2017/136659