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1. (EP3383398) CYCLING THERAPY USING 3-(5-AMINO-2-METHYL-4-OXO-4H-QUINAZOLIN-3-YL)-PIPERIDINE-2,6-DIONE

Office : European Patent Office
Application Number: 16819227 Application Date: 01.12.2016
Publication Number: 3383398 Publication Date: 10.10.2018
Publication Kind : A1
Designated States: AL, AT, BA, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, ME, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR
Prior PCT appl.: Application Number:US2016064392 ; Publication Number: Click to see the data
IPC:
A61K 31/517
A61P 35/00
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
495
having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505
Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
517
ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
CPC:
A61K 31/517
A61K 9/0053
A61P 35/00
Applicants: CELGENE CORP
Inventors: HAGNER PATRICK
GANDHI ANITA
POURDEHNAD MICHAEL
Priority Data: 201562262263 02.12.2015 US
2016064392 01.12.2016 US
Title: (DE) ZYKLUSTHERAPIE UNTER VERWENDUNG VON 3-(5-AMINO-2-METHYL-4-OXO-4H-CHINAZOLIN-3-YL)-PIPERIDIN-2,6-DION
(EN) CYCLING THERAPY USING 3-(5-AMINO-2-METHYL-4-OXO-4H-QUINAZOLIN-3-YL)-PIPERIDINE-2,6-DIONE
(FR) THÉRAPIE PRÉSENTANT DES CYCLES D'ADMINISTRATION DE 3-(5-AMINO-2-MÉTHYL-4-OXO-4H-QUINAZOLIN-3-YL)-PIPÉRIDINE-2,6-DIONE
Abstract:
(EN) Provided herein are methods of treating, preventing and/or managing cancer, including lymphoma, which comprise administering to a patient 3-(5-amino-2-methyl-4- oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione, or an enantiomer or a mixture of enantiomers thereof, or a pharmaceutically acceptable salt, solvate, hydrate, co-crystal, clathrate, or polymorph thereof in a cyclic therapy regimen.
(FR) L'invention concerne des méthodes de traitement, de prévention et/ou de prise en charge d'un cancer, qui consistent à administrer à un patient de la 3-(5-amino-2-méthyl-4-oxo-4H-quinazolin-3-yl)-pipéridine-2,6-dione, ou un énantiomère ou un mélange d'énantiomères de celle-ci, ou un sel, un solvate, un hydrate, un co-crystal, un clathrate ou un polymorphe pharmaceutiquement acceptable de celle-ci.
Also published as:
AU2016364753CA3006758SG11201804367PIL259597KR1020180088401MX2018006779
BR112018010964EA201891289WO/2017/096024