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1. EP3336100 - PEPTIDE HAVING EFFECT OF PREVENTING OR TREATING CENTRAL NERVOUS SYSTEM DISEASES AND PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING CENTRAL NERVOUS SYSTEM DISEASES, CONTAINING SAME AS ACTIVE INGREDIENT

Office
European Patent Office
Application Number 16839533
Application Date 19.08.2016
Publication Number 3336100
Publication Date 20.06.2018
Publication Kind B1
IPC
A61P 25/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
A61K 38/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
C07K 14/705
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
705Receptors; Cell surface antigens; Cell surface determinants
C12N 9/10
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
10Transferases (2.)
CPC
A61K 38/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
A61P 25/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
C07K 14/70521
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
705Receptors; Cell surface antigens; Cell surface determinants
70503Immunoglobulin superfamily
70521CD28, CD152
C07K 2319/10
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
2319Fusion polypeptide
01containing a localisation/targetting motif
10containing a tag for extracellular membrane crossing, e.g. TAT or VP22
C12N 9/104
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9Enzymes; Proenzymes; Compositions thereof
10Transferases (2.)
1025Acyltransferases (2.3)
104Aminoacyltransferases (2.3.2)
A61K 38/177
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17from animals; from humans
177Receptors; Cell surface antigens; Cell surface determinants
Applicants IUCF HYU
Inventors CHOI JE-MIN
LIM SANGHO
Designated States
Priority Data 20150117966 21.08.2015 KR
Title
(DE) PEPTID MIT WIRKUNG ZUR VORBEUGUNG ODER BEHANDLUNG VON KRANKHEITEN DES ZENTRALEN NERVENSYSTEMS UND PHARMAZEUTISCHE ZUSAMMENSETZUNG ZUR VORBEUGUNG UND BEHANDLUNG VON KRANKHEITEN DES ZENTRALEN NERVENSYSTEMS DAMIT ALS WIRKSTOFF
(EN) PEPTIDE HAVING EFFECT OF PREVENTING OR TREATING CENTRAL NERVOUS SYSTEM DISEASES AND PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING CENTRAL NERVOUS SYSTEM DISEASES, CONTAINING SAME AS ACTIVE INGREDIENT
(FR) PEPTIDE AYANT POUR EFFET DE PRÉVENIR OU TRAITER DES MALADIES DU SYSTÈME NERVEUX CENTRAL ET COMPOSITION PHARMACEUTIQUE POUR LA PRÉVENTION ET LE TRAITEMENT DE MALADIES DU SYSTÈME NERVEUX CENTRAL, CONTENANT CE DERNIER EN TANT QUE PRINCIPE ACTIF
Abstract
(EN) The present invention has a function of enabling the penetration of the blood-brain barrier and the blood-spinal cord barrier of the central nervous system, which have not been significantly penetrated, with excellent efficiency, thereby enabling a rapid, quick, and more efficient therapeutic effect to be obtained through low dose administration. In addition, the present invention enables local administration unlike conventional therapeutic agents, thereby decreasing side effects, and enables local administration of a therapeutic agent at a high concentration, thereby enabling potentially new treatments and prescriptions.
(FR) La présente invention a pour fonction de permettre la pénétration de la barrière hémato-encéphalique et la barrière sang-moelle épinière du système nerveux central, qui n'ont pas été significativement pénétrées, avec une excellente efficacité, ce qui permet d'obtenir un effet thérapeutique rapide, prompt et plus efficace par une administration à faible dose. En outre, la présente invention permet une administration locale à la différence des agents thérapeutiques classiques, ce qui permet de réduire les effets secondaires, et permet l'administration locale d'un agent thérapeutique à une concentration élevée, ce qui permet potentiellement de nouveaux traitements et de nouvelles prescriptions.