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1. EP3271402 - ANTIBODIES TOWARDS AN EXTRACELLULAR REGION OF NBCN1

Office European Patent Office
Application Number 16715793
Application Date 16.03.2016
Publication Number 3271402
Publication Date 24.01.2018
Publication Kind A1
IPC
C07K 16/44
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
44against material not provided for elsewhere
A61K 39/395
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
CPC
C07K 16/28
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
A61K 39/39558
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
395Antibodies
39533against materials from animals
39558against tumor tissues, cells, antigens
A61K 45/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A61K 2039/505
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
505comprising antibodies
C07K 16/44
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
44against material not provided for elsewhere ; , e.g. haptens, metals, DNA, RNA, amino acids
C07K 2317/76
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
2317Immunoglobulins specific features
70characterized by effect upon binding to a cell or to an antigen
76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Applicants AARHUS UNIV
Inventors BØDTKJER EBBE BRIGGS
Designated States
Priority Data PA201570148 16.03.2015 DK
Title
(DE) ANTIKÖRPER GEGEN EINE EXTRAZELLULÄRE REGION VON NBCN1
(EN) ANTIBODIES TOWARDS AN EXTRACELLULAR REGION OF NBCN1
(FR) ANTICORPS DIRIGÉS CONTRE UNE RÉGION EXTRACELLULAIRE DE NBCN1
Abstract
(EN)
The present application discloses antibodies or antigen binding fragment thereof specifically recognizing and binding an extracellular polypeptide region of human NBCnl. Experimental data are detailed for mouse NBCnl antibodies. The medical use of such antibodies is claimed, in particular for the treatment of hyperproliferative disorders, such as cancer, or atherosclerosis and/or restenosis.

(FR)
La présente invention concerne des anticorps ou un fragment de liaison d'antigène de celui-ci reconnaissant spécifiquement une région polypeptidique extracellulaire de NBCnl humaine et se liant spécifiquement à ladite région. Des données expérimentales sont détaillées pour des anticorps NBCnl de souris. L'utilisation médicale de tels anticorps est revendiquée, en particulier pour le traitement de troubles hyperprolifératifs, tels que le cancer, ou l'athérosclérose et/ou la resténose.

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