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1. (EP2305701) Tuberculosis antigen detection assays and vaccines

Office : European Patent Office
Application Number: 10180752 Application Date: 29.06.2006
Publication Number: 2305701 Publication Date: 06.04.2011
Publication Kind : A1
IPC:
C07K 14/35
A61K 39/04
C12Q 1/68
G01N 33/569
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
195
from bacteria
35
from Mycobacteriaceae (F)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
02
Bacterial antigens
04
Mycobacterium, e.g. Mycobacterium tuberculosis
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
68
involving nucleic acids
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
569
for micro-organisms, e.g. protozoa, bacteria, viruses
CPC:
G01N 33/5695
A61K 39/00
A61K 2039/53
C07K 14/35
C07K 2319/00
C12Q 1/6883
C12Q 2600/158
G01N 33/6893
G01N 2800/12
Applicants: FORSYTH DENTAL IN RY FOR CHILDREN FA
Inventors: CAMPOS NETO ANTONIO
KASHINO SUELY
Priority Data: 06774367 29.06.2006 EP
69643905 01.07.2005 US
71706205 14.09.2005 US
Title: (DE) Assays zur Detektion von Tuberkuloseantigenen und Impfstoffe
(EN) Tuberculosis antigen detection assays and vaccines
(FR) Essais de détéction d'antigenes de la tuberculose et vaccins
Abstract: front page image
(EN) The present invention relates to isolated Tuberculosis (TB) antigens that are useful in therapeutic and vaccine compositions for stimulating a TB specific immunological response. The identified antigens are also useful in diagnostic assays to determine the presence of active TB in an individual. Accordingly, the present invention includes polypeptide molecules, nucleic acid molecules, vaccine compositions, diagnostic assays, and methods of diagnosis and monitoring treatment related to these TB antigens.
Also published as:
EP1910410BRPI0613168-9ZA2008/00401CN101365714IN5070/KOLNP/2007WO/2007/005627