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1. (EP1989214) PROCESS FOR PREPARING AN A2A-ADENOSINE RECEPTOR AGONIST AND ITS POLYMORPHS

Office : European Patent Office
Application Number: 07763545 Application Date: 02.02.2007
Publication Number: 1989214 Publication Date: 12.11.2008
Publication Kind : B8
Designated States: AL, AT, BA, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, NL, PL, PT, RO, RS, SE, SI, SK, TR
Prior PCT appl.: Application Number:US2007003022 ; Publication Number: Click to see the data
IPC:
C07H 19/167
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
H
SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
19
Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro derivatives thereof
02
sharing nitrogen
04
Heterocyclic radicals containing only nitrogen as ring hetero atom
16
Purine radicals
167
with ribosyl as the saccharide radical
CPC:
C07H 19/16
C07H 19/167
Applicants: GILEAD SCIENCES INC
Inventors: ZABLOCKI JEFF
ELZEIN ELFATIH
SEEMAYER ROBERT
LEMONS TRAVIS
Priority Data: 2007003022 02.02.2007 US
76511406 03.02.2006 US
80185706 18.05.2006 US
Title: (DE) VERFAHREN ZUR HERSTELLUNG EINES A2A-ADENOSINREZEPTORAGONISTEN SOWIE DESSEN POLYMORPHE
(EN) PROCESS FOR PREPARING AN A2A-ADENOSINE RECEPTOR AGONIST AND ITS POLYMORPHS
(FR) PROCEDE DE PREPARATION D'UN AGONISTE DE RECEPTEUR A2A-ADENOSINE ET SES POLYMORPHES
Abstract: front page image
(EN) Disclosed is a synthesis suitable for large scale manufacture of an A2A- adenosine receptor agonist, and also relates to polymorphs of that compound, and to methods of isolating a specific polymorph.
(FR) La présente invention concerne une synthèse appropriée à la fabrication à grande échelle d'un agoniste de récepteur A2A-adénosine et concerne également les polymorphes de ce composé et les procédés d'isolement d'un polymorphe spécifique.
Also published as:
NO20083395MXMX/a/2008/009879IL193153ZA2008/06666JP2009525347RU0002447081
EP2581381CN101379073CA2640089KR1020130130868NZ570239ES2593028
AU2007212542IL252700WO/2007/092372