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1. EP1896589 - NOVEL GENES AND PROTEINS OF BRACHYSPIRA PILOSICOLI AND USE OF SAME FOR DIAGNOSIS AND THERAPY

Office
European Patent Office
Application Number 06762123
Application Date 21.06.2006
Publication Number 1896589
Publication Date 12.03.2008
Publication Kind A2
IPC
C12N 15/31
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
11DNA or RNA fragments; Modified forms thereof
31Genes encoding microbial proteins, e.g. enterotoxins
A61K 39/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
02Bacterial antigens
C07K 14/20
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
195from bacteria
20from Spirochaetales (O), e.g. Treponema, Leptospira
C07K 16/12
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
12against material from bacteria
C12N 15/85
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
79Vectors or expression systems specially adapted for eukaryotic hosts
85for animal cells
C12Q 1/68
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
CPC
C07K 14/20
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
195from bacteria
20from Spirochaetales (O), e.g. Treponema, Leptospira
A61K 39/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
A61K 2039/53
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
51comprising whole cells, viruses or DNA/RNA
53DNA (RNA) vaccination
Applicants NOVARTIS AG
UNIV MURDOCH
Inventors BELLGARD MATTHEW
HAMPSON DAVID JOHN
LA TOM
Designated States
Priority Data 2005903317 23.06.2005 AU
Title
(DE) NEUE GENE UND PROTEINE AUS BRACHYSPIRA PILOSICOLI UND VERWENDUNG DAVON ZUR DIAGNOSE UND THERAPIE
(EN) NOVEL GENES AND PROTEINS OF BRACHYSPIRA PILOSICOLI AND USE OF SAME FOR DIAGNOSIS AND THERAPY
(FR) GENES ET PROTEINES DE BRACHYSPIRA PILOSICOLI ET UTILISATION DE CEUX-CI POUR DES DIAGNOSTIC ET TRAITEMENT
Abstract
(EN) Novel polynucleotide and amino acids of Brachyspira pilosicoli are described. These sequences are useful for diagnosis of B. pilosicoli disease in animals and as a therapeutic treatment or prophylactic treatment of B. pilosicoli disease in animals. These sequences may also be useful for diagnostic and therapeutic and/or prophylactic treatment of diseases in animals caused by other Brachyspira species, including B. intermedia, B. alvinipulli, B. aalborgi, B. innocens, B. murdochii, and B. hyodysenteriae.
(FR) L'invention concerne un polynucléotide et des acides aminés de Brachyspira pilosicoli. Ces séquences sont utiles pour le diagnostic de la maladie B. pilosicoli chez des animaux et comme traitement thérapeutique ou prophylactique de la maladie B. pilosicoli chez des animaux. Ces séquences peuvent être utiles également pour le diagnostic et le traitement thérapeutique et/ou prophylactique de maladies chez des animaux engendrées par d'autres espèces de Brachyspira, notamment B. intermedia, B. alvinipulli, B. aalborgi, B. innocens, B. murdochii, et B. hyodysenteriae.