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1. EP1807211 - A HANDHELD AND PORTABLE MICROFLUIDIC DEVICE TO AUTOMATICALLY PREPARE NUCLEIC ACIDS FOR ANALYSIS

Office
European Patent Office
Application Number 05796161
Application Date 09.09.2005
Publication Number 1807211
Publication Date 18.07.2007
Publication Kind A1
IPC
B01L 3/02
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
3Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
02Burettes; Pipettes
B01L 99/00
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
99Subject matter not provided for in other groups of this subclass
G01N 1/10
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
1Sampling; Preparing specimens for investigation
02Devices for withdrawing samples
10in the liquid or fluent state
G01N 1/22
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
1Sampling; Preparing specimens for investigation
02Devices for withdrawing samples
22in the gaseous state
CPC
B01L 3/0217
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
3Containers or dishes for laboratory use, e.g. laboratory glassware
02Burettes; Pipettes
021Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
0217of the plunger pump type
B01L 3/0293
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
3Containers or dishes for laboratory use, e.g. laboratory glassware
02Burettes; Pipettes
0289Apparatus for withdrawing or distributing predetermined quantities of fluid
0293for liquids
B01L 3/502
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
3Containers or dishes for laboratory use, e.g. laboratory glassware
50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
502with fluid transport, e.g. in multi-compartment structures
B01L 3/5027
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
3Containers or dishes for laboratory use, e.g. laboratory glassware
50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
502with fluid transport, e.g. in multi-compartment structures
5027by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
B01L 9/527
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
9Supporting devices; Holding devices
52Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips
527for microfluidic devices, e.g. used for lab-on-a-chip
B01L 2300/0681
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2300Additional constructional details
06Auxiliary integrated devices, integrated components
0681Filter
Applicants MICROFLUIDIC SYSTEMS INC
Inventors YUAN BOB
AFLATOONI NIMA
Designated States
Priority Data 60899904 09.09.2004 US
Title
(DE) TRAGBARE HAND-MIKROFLUIDVORRICHTUNG ZUR AUTOMATISCHEN HERSTELLUNG VON NUKLEINSÄUREN ZUR ANALYSE
(EN) A HANDHELD AND PORTABLE MICROFLUIDIC DEVICE TO AUTOMATICALLY PREPARE NUCLEIC ACIDS FOR ANALYSIS
(FR) DISPOSITIF MICROFLUIDIQUE MANUEL ET PORTABLE SERVANT A LA PREPARATION AUTOMATIQUE D'ACIDES NUCLEIQUES POUR ANALYSE
Abstract
(EN) A handheld and portalbe extraction device (10) is directed to a microfluidic-based system to be used in the field to extract and purify an analyte, preferably a nucleic acid, from a fluid-based sample. Preferably, the fluid-based sample is water-based. The fluid-based sample can also be a biological fluid sample. The handheld and portable extraction device includes a syringe-like device (14) coupled to a purification chip (48). The purification chip is preferably included within a chip block (40), which is removable from the remaining portion of the handheld and portable extraction device. The analyte collected within the purification chip can be later removed and collected for analysis.
(FR) Cette invention concerne un dispositif d'extraction manuel et portable (10) pour un système microfluidique conçu pour être utilisé dans le domaine de l'extraction et de la purification d'un analyte, tel que de préférence un acide nucléique, contenu dans un échantillon à base de fluide. L'échantillon à base de fluide est de préférence à base d'eau. L'échantillon à base de fluide peut également être un échantillon de fluide biologique. Ce dispositif d'extraction manuel et portable comprend un dispositif du type seringue (14) couplé à une puce de purification (48). La puce de purification est de préférence incluse dans un bloc à puce (40), qui peut être retiré de la partie restante du dispositif d'extraction manuel et portable. L'analyte recueilli dans la puce de purification peut ensuite être retiré et recueilli pour analyse.
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