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1. EP1633425 - KINETIC ISOLATION PRESSURIZATION

Office
European Patent Office
Application Number 04752916
Application Date 21.05.2004
Publication Number 1633425
Publication Date 15.03.2006
Publication Kind A4
IPC
A61M 29/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
29Dilators with or without means for introducing media, e.g. remedies
A61M
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
A61M 25/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
25Catheters; Hollow probes
A61M 25/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
25Catheters; Hollow probes
10Balloon catheters
A61M 31/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
31Devices for introducing or retaining media, e.g. remedies, in cavities of the body
CPC
A61M 25/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
25Catheters; Hollow probes
10Balloon catheters
A61M 2025/0057
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
25Catheters; Hollow probes
0043characterised by structural features
0057Catheters delivering medicament other than through a conventional lumen, e.g. porous walls or hydrogel coatings
A61M 2025/105
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
25Catheters; Hollow probes
10Balloon catheters
1043with special features or adapted for special applications
105having a balloon suitable for drug delivery, e.g. by using holes for delivery, drug coating or membranes
Applicants ATRIUM MEDICAL CORP
Inventors HERWECK STEVE A
MARTAKOS PAUL
MOODIE GEOFFREY
LABRECQUE ROGER
Designated States
Priority Data 10444863 22.05.2003 US
Title
(DE) KINETISCHE ISOLATIONSDRUCKBELASTUNG
(EN) KINETIC ISOLATION PRESSURIZATION
(FR) APPORT CINETIQUE D'UN FLUIDE SOUS PRESSION DANS UN SITE ISOLE
Abstract
(EN) A method of delivering a therapeutic agent to a targeted location within a patient efficiently delivers the agent with a reduced systemic effect. The method includes providing a non-perforated delivery device (10) having at least one wall (12) through which a fluid at first fluid pressure can pass through. The non-perforated delivery device (10) is positioned to provide a radial fluid force against the targeted location. The fluid, including at least one therapeutic agent, is supplied to the therapeutic agent delivery device (10) at the first fluid pressure. The fluid passes through the at least one wall (12) of the delivery device (10) to create a semi-confined space external to the delivery device (10) at a second fluid pressure. The delivery device (10) applies the radial fluid force against the semi-confined space and the fluid disposed therein while simultaneously facilitating the fluid passing through the delivery device (10) to maintain the second fluid pressure in the semi-confined space at the targeted location. The fluid contains at least one therapeutic agent that is distributed to the targeted location in a substantially uniform distribution in an amount sufficient to create a therapeutic effect modulatable by the fluid pressure and a dwell time.
(FR) Procédé d'apport d'un agent thérapeutique dans un site cible dans le corps d'un patient, ledit agent étant apporté de manière efficace avec un effet systémique réduit. Ledit procédé repose sur l'utilisation d'un dispositif d'apport non perforé possédant au moins une paroi que peut traverser un fluide à une première pression. Ce dispositif d'apport non perforé est placé de manière à fournir une force de fluide radiale contre le site cible. Le fluide, contenant au moins un agent thérapeutique, est amené au dispositif d'apport d'agent thérapeutique à la première pression. Le fluide passe à travers la paroi du dispositif d'apport pour créer un espace semi-confiné externe par rapport au dispositif d'apport, à une seconde pression du fluide. Le dispositif d'apport exerce la force de fluide radiale contre l'espace semi-confiné et le fluide se trouvant dans ledit espace, tout en facilitant simultanément le passage du fluide à travers le dispositif d'apport pour maintenir la seconde pression de fluide dans l'espace semi-confiné sur le site cible. Le fluide contient au moins un agent thérapeutique qui est apporté dans le site cible de manière sensiblement homogène, en quantité suffisante pour créer un effet thérapeutique pouvant être modulé par la pression de fluide et la durée de pénétration.