EP1174506 C-terminal Erns peptide and analogues thereof

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European Patent Office

Application Number 00202255

Application Date 28.06.2000

Publication Number 1174506

Publication Date 23.01.2002

Publication Kind A1

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Applicants STICHTING DIENST LANDBOUWKUNDI

Inventors LANGEDIJK JOHANNES PETRUS MARI

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Priority Data 00202255 28.06.2000 EP

Title

(DE) C-terminales Erns-Peptide und Analoge davon

(EN) C-terminal Erns peptide and analogues thereof

(FR) Le peptide C-terminal de Erns et ses analogues

Abstract

(EN) The invention relates to peptides derived from or similar to the E protein of pestiviruses for type -specific diagnosis of infection, for eliciting antibiotic activity and for transport of substances into a cell. For among others these purposes the invention provides an isolated, synthetic or recombinant protein module or functional equivalent thereof comprising an amino acid sequence that is at least 75% identical to an amino acid sequence of a peptide located from at about amino acid position 194 to 220 in a pestiviral E protein.

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38	Medicinal preparations containing peptides

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39	Medicinal preparations containing antigens or antibodies

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39	Medicinal preparations containing antigens or antibodies
12	Viral antigens

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
P	SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31	Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
04	Antibacterial agents

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
K	PEPTIDES
14	Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
005	from viruses
08	RNA viruses
115	Paramyxoviridae, e.g. parainfluenza virus
135	Respiratory syncytial virus

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1. EP1174506 - C-terminal Erns peptide and analogues thereof

C	CHEMISTRY; METALLURGY
12	BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N	MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15	Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09	Recombinant DNA-technology

G	PHYSICS
01	MEASURING; TESTING
N	INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33	Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48	Biological material, e.g. blood, urine; Haemocytometers
50	Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53	Immunoassay; Biospecific binding assay; Materials therefor
569	for microorganisms, e.g. protozoa, bacteria, viruses

C	CHEMISTRY; METALLURGY
12	BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N	MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
2770	ssRNA Viruses positive-sense
00011	ssRNA Viruses positive-sense
24011	Flaviviridae
24311	Pestivirus, e.g. bovine viral diarrhea virus
24322	New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

C	CHEMISTRY; METALLURGY
12	BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N	MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
2770	ssRNA Viruses positive-sense
00011	ssRNA Viruses positive-sense
24011	Flaviviridae
24311	Pestivirus, e.g. bovine viral diarrhea virus
24322	New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes