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1. (EP0998487) INCORPORATION OF PHARMACOLOGICALLY ACTIVE AMINO ACID ANALOGUES INTO PROTEINS

Application Number: 98936310 Application Date: 05.06.1998
Publication Number: 0998487 Publication Date: 10.05.2000
Publication Kind : A2
Designated States: AT,BE,CH,DE,DK,ES,FR,GB,IE,IT,LI,NL,SE
Prior PCT appl.: Application Number:EP1998003398 ; Publication Number: Click to see the data
IPC:
A 61K
C 07K
A61K 47/48
C 07K
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
48
the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
4
Peptides having up to 20 amino acids in an undefined or only partially defined sequence; Derivatives thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
48
the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
CPC:
A61K 47/48238
Applicants: MAX PLANCK GESELLSCHAFT
Inventors: BUDISA NEDILJKO
HUBER ROBERT
MINKS CAROLIN
MORODER LUIS
Priority Data: 19724670 11.06.1997 DE
9803398 05.06.1998 EP
Title: (DE) INKORPORATION VON PHARMAKOLOGISCH WIRKSAMEN AMINOSÄUREANALOGA IN PROTEINE
(EN) INCORPORATION OF PHARMACOLOGICALLY ACTIVE AMINO ACID ANALOGUES INTO PROTEINS
(FR) INCORPORATION D'ANALOGUES D'ACIDES AMINES A ACTION PHARMACOLOGIQUE DANS DES PROTEINES
Abstract:
(DE) Die Erfindung betrifft eine pharmazeutische Zusammensetzung, die als Wirkstoff mindestens ein pharmakologisch wirksames Aminosäureanalogon eingebaut in ein Peptid oder Polypeptid als Träger oder Vehikel enthält. Weiterhin werden Verfahren zur Herstellung solcher pharmazeutischer Zusammensetzungen offenbart.
(EN) The invention relates to a pharmaceutical compound containing as an active ingredient at least one pharmacologically active amino acid analogue incorporated into a peptide or polypeptide as carrier or vehicle. The invention also relates to methods for producing such pharmaceutical compounds.
(FR) L'invention concerne une composition pharmaceutique qui contient, comme principe actif, au moins un analogue d'acide aminé actif pharmacologiquement, incorporé dans un peptide ou polypeptide servant d'excipient ou de véhicule. L'invention concerne également un procédé de production de telles compositions pharmaceutiques.