EP0600983 A FERMENTATION PROCESS FOR PRODUCING NATAMYCIN

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European Patent Office

Application Number 92917836

Application Date 05.08.1992

Publication Number 0600983

Publication Date 15.06.1994

Publication Kind B1

IPC

CPC

Applicants BIO TECH RESOURCES

Inventors EISENSCHINK MICHAEL ALLEN
MILLIS JAMES R
OLSON PHILLIP TERRY

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Priority Data 74054591 05.08.1991 US
9206323 05.08.1992 US

Title

(DE) FERMENTATIONSPROZESS ZUR HERSTELLUNG VON NATAMYCIN

(EN) A FERMENTATION PROCESS FOR PRODUCING NATAMYCIN

(FR) PROCEDE DE FERMENTATION POUR LA PRODUCTION DE NATAMYCINE

Abstract

(EN) A natamycin producing $i(Streptomyces) species ferments to produce natamycin. A spore suspension of the $i(Streptomyces) species is propagated in a predetermined medium to obtain a quantity of $i(Streptomyces) cells. The $i(Streptomyces) cells ferment in a predetermined production medium to produce a recoverable amount of natamycin.

(FR) L'invention concerne un procédé de fermentation d'une espèce de $i(Streptomyces) afin de produire de la natamicyne. Une suspension de spores de l'espèce de $i(Streptomyces) se propage dans un milieu prédéterminé afin d'obtenir une quantité de cellules de $i(Streptomyces). Les cellules de $i(Streptomyces) fermentent dans un milieu de production prédéterminé afin de produire une quantité récupérable de natamycine.

C	CHEMISTRY; METALLURGY
12	BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P	FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
19	Preparation of compounds containing saccharide radicals
44	Preparation of O-glycosides, e.g. glucosides
60	having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
62	the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin

C	CHEMISTRY; METALLURGY
12	BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P	FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
19	Preparation of compounds containing saccharide radicals
44	Preparation of O-glycosides, e.g. glucosides
60	having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
62	the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin

C	CHEMISTRY; METALLURGY
12	BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P	FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
19	Preparation of compounds containing saccharide radicals
44	Preparation of O-glycosides, e.g. glucosides
60	having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
62	the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
626	Natamycin; Pimaricin; Tennecetin

C	CHEMISTRY; METALLURGY
12	BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P	FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
19	Preparation of compounds containing saccharide radicals
44	Preparation of O-glycosides, e.g. glucosides
60	having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
62	the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
626	Natamycin; Pimaricin; Tennecetin

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1. EP0600983 - A FERMENTATION PROCESS FOR PRODUCING NATAMYCIN