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1. (EP2271665) HIGHLY BRIDGED PEPTIDES FROM ACTINOMADURA NAMIBIENSIS

Office : European Patent Office
Application Number: 09728150 Application Date: 18.03.2009
Publication Number: 2271665 Publication Date: 12.01.2011
Publication Kind : B1
Designated States: AL,AT,BA,BE,BG,CH,CY,CZ,DE,DK,EE,ES,FI,FR,GB,GR,HR,HU,IE,IS,IT,LI,LT,LU,LV,MC,MK,MT,NL,NO,PL,PT,RO,RS,SE,SI,SK,TR
Prior PCT appl.: Application Number:EP2009001982 ; Publication Number: Click to see the data
IPC:
C07K 14/36
A61K 38/10
A61P 31/04
A61P 31/12
C07K 7/08
C12P 21/02
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
195
from bacteria
36
from Actinomyces; from Streptomyces (G)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
04
Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
10
Peptides having 12 to 20 amino acids
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31
Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
04
Antibacterial agents
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31
Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12
Antivirals
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
7
Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
04
Linear peptides containing only normal peptide links
08
having 12 to 20 amino acids
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
21
Preparation of peptides or proteins
02
having a known sequence of two or more amino acids, e.g. glutathione
CPC:
C07K 7/08
C07K 14/36
Applicants: SANOFI SA
Inventors: BROENSTRUP MARK
GUEHRING HANS
HOFFMANN HOLGER
WINK JOACHIM
SUESSMUTH RODERICH
SCHMIEDERER TIMO
Priority Data: 08290324 null
EP20080290324 null
EP2009001982 null
EP20090728150 null
WO2009EP01982 null
08290324 02.04.2008 EP
09728150 18.03.2009 EP
09728150 18.03.2009 EP
Title: (DE) STARK VERBRÜCKTE PEPTIDE AUS DER ACTINOMADURA NAMIBIENSIS
(EN) HIGHLY BRIDGED PEPTIDES FROM ACTINOMADURA NAMIBIENSIS
(FR) PEPTIDES HAUTEMENT PONTÉS PROVENANT D'ACTINOMADURA NAMIBIENSIS
Abstract:
(EN) The invention refers to so-called Labyrinthopeptin derivatives of the formula (I) wherein {A}, {B}, {C}, R1-R6, m and n are as defined herein, obtainable from microorganism strain Actinomadura namibiensis (DSM 6313), its use for the treatment of bacterial infections, viral infections and/or pain, a pharmaceutical composition comprising it, prepro-Labyrinthopeptin, pro-Labyrinthopeptin, and DNA coding for prepro-Labyrinthopeptin and pro-Labyrinthopeptin.
(FR) L'invention porte sur des dérivés dits de Labyrinthopeptine représentés par la formule (I) dans laquelle {A}, {B}, {C}, R1-R6, m et n sont tels que définis présentement, pouvant être obtenus à partir de la souche de micro-organisme Actinomadura namibiensis (DSM 6313), sur leur utilisation pour le traitement d'infections bactériennes, d'infections virales et/ou de la douleur, sur une composition pharmaceutique les comprenant, sur une prépro-Labyrinthopeptine, sur une pro-Labyrinthopeptine et sur un ADN codant pour la prépro-Labyrinthopeptine et la pro-Labyrinthopeptine.
Also published as:
AR071125IL208239SG164966JP2011516048MXMX/a/2010/010115US20110144001
RU2010144778CN102046652CA2720173RU0002498995KR1020110014563AU2009231118
MYPI 2010004183TH106972IN6237/CHENP/2010WO/2009/121483