Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (EP2060584) Method for the production of proteins with chemically functionalized N-termini

Office : European Patent Office
Application Number: 07020231 Application Date: 16.10.2007
Publication Number: 2060584 Publication Date: 20.05.2009
Publication Kind : A1
Designated States: AL,AT,BA,BE,BG,CH,CY,CZ,DE,DK,EE,ES,FI,FR,GB,GR,HR,HU,IE,IS,IT,LI,LT,LU,LV,MC,MK,MT,NL,PL,PT,RO,RS,SE,SI,SK,TR
IPC:
C07K 14/485
C07K 1/107
C12P 1/04
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
475
Growth factors; Growth regulators
485
Epidermal growth factor (EGF) (urogastrone)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
1
General processes for the preparation of peptides
107
by chemical modification of precursor peptides
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
1
Preparation of compounds or compositions, not provided for in groups C12P3/-C12P39/121; General processes for the preparation of compounds or compositions by using micro-organisms or enzymes
04
by using bacteria
CPC:
C07K 14/485
C12P 21/005
C12P 21/02
Applicants: MAX PLANCK GESELLSCHAFT
Inventors: BUDISA NEDILJKO
MERKEL LARS
CHEBURKIN YURI
ULLRICH AXEL
KNYAZEV PIOTR
WILTSCHI BIRGIT
Priority Data: 07020231 16.10.2007 EP
Title: (DE) Verfahren zur Herstellung von Proteinen mit chemisch funktionalisierten N-Termini
(EN) Method for the production of proteins with chemically functionalized N-termini
(FR) Procédé pour la production de protéines dotées de n-terminaisons à fonction chimique
Abstract: front page image
(EN) The present invention refers to the production of N-terminally modified polypeptides, wherein an N-terminal methionine residue is replaced by a non-genetically encoded amino acid residue. The non-genetically coded amino acid residue may comprise a functional chemical moiety for coupling two heterologous molecules, e.g. reporter or effector molecules.