EA201692255 УЛУЧШЕННЫЕ ФОРМЫ СЕЛЕКТИВНОГО ИНГИБИТОРА PI3K-ДЕЛЬТА ДЛЯ ПРИМЕНЕНИЯ В ФАРМАЦЕВТИЧЕСКИХ ПРЕПАРАТАХ

Settings

Stemming

Single Family Member

Include NPL

Feedback

Goto Application

Office

Eurasian Patent Organization

Application Number 201692255

Application Date 26.05.2015

Publication Number 201692255

Publication Date 28.04.2017

Grant Number 032506

Grant Date 28.06.2019

Publication Kind B1

IPC

CPC

View more classifications

View less classifications

Applicants РИЗЕН ФАРМАСЬЮТИКАЛЗ СА
RHIZEN PHARMACEUTICALS SA

Inventors Ваккаланка Сваруп Кумар Венката Сатья
VAKKALANKA Swaroop, Kumar, Venkata, Satya

Agents Нилова Мария Иннокентьевна
Nilova Maria, I.

Priority Data 2596/CHE/2014 27.05.2014 IN
2597/CHE/2014 27.05.2014 IN

Title

(RU) УЛУЧШЕННЫЕ ФОРМЫ СЕЛЕКТИВНОГО ИНГИБИТОРА PI3K-ДЕЛЬТА ДЛЯ ПРИМЕНЕНИЯ В ФАРМАЦЕВТИЧЕСКИХ ПРЕПАРАТАХ

Abstract

(RU)

Изобретение относится к твердофазным формам соли п-толуолсульфоновой кислоты (ПТСК) селективного ингибитора PI3K-дельта (S)-2-(1-(4-амино-3-(3-фтор-4-изопропоксифенил)-1H-пиразоло[3,4-d]пиримидин-1-ил)этил)-6-фтор-3-(3-фторфенил)-4H-хромен-4-она (TGR-1202). Изобретение также относится к способам получения указанных соединений, содержащим их фармацевтическим композициям и способам лечения опосредованных киназой PI3K (фосфатидилинозитол-3-киназой).

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
D	HETEROCYCLIC COMPOUNDS
487	Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/-C07D477/183
02	in which the condensed system contains two hetero rings
04	Ortho-condensed systems

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
D	HETEROCYCLIC COMPOUNDS
487	Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/-C07D477/183
02	in which the condensed system contains two hetero rings
04	Ortho-condensed systems

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
D	HETEROCYCLIC COMPOUNDS
487	Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by C07D451/00 - C07D477/00
02	in which the condensed system contains two hetero rings
04	Ortho-condensed systems

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
B	GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
2200	Indexing scheme relating to specific properties of organic compounds
13	Crystalline forms, e.g. polymorphs

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
P	SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
29	Non-central analgesic, antipyretic or anti-inflammatory agents, e.g antirheumatic agents; Non-steroidal anti-inflammatory drugs (NSAIDs)

Processing

National Phase Entries

Authority File

Settings

Feedback

Goto Application

1. EA201692255 - УЛУЧШЕННЫЕ ФОРМЫ СЕЛЕКТИВНОГО ИНГИБИТОРА PI3K-ДЕЛЬТА ДЛЯ ПРИМЕНЕНИЯ В ФАРМАЦЕВТИЧЕСКИХ ПРЕПАРАТАХ

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients
33	Heterocyclic compounds
395	having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495	having six-membered rings with two ; or more; nitrogen atoms as the only ring heteroatoms, e.g. piperazine ; or tetrazines
505	Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
519	ortho- or peri-condensed with heterocyclic rings

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
C	ACYCLIC OR CARBOCYCLIC COMPOUNDS
309	Sulfonic acids; Halides, esters, or anhydrides thereof
01	Sulfonic acids
28	having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
29	of non-condensed six-membered aromatic rings
30	of six-membered aromatic rings substituted by alkyl groups

Y	SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
02	TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
A	TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
50	in human health protection, e.g. against extreme weather
30	Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change