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1. DK3319612 - OXYSTEROLER OG FREMGANSMÅDER TIL ANVENDELSE DERFOR

Office
Denmark
Application Number 16821926
Application Date 06.07.2016
Publication Number 3319612
Publication Date 23.08.2021
Grant Number 3319612
Grant Date 23.08.2021
Publication Kind T3
IPC
A61K 31/567
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
56Compounds containing cyclopentahydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
565not substituted in position 17 beta by a carbon atom, e.g. oestrane, oestradiol
567substituted in position 17 alpha, e.g. mestranol, norethandrolone
A61K 31/566
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
56Compounds containing cyclopentahydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
565not substituted in position 17 beta by a carbon atom, e.g. oestrane, oestradiol
566having an oxo group in position 17, e.g. oestrone
A61P 3/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3Drugs for disorders of the metabolism
A61P 25/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
C07J 9/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
JSTEROIDS
9Normal steroids containing carbon, hydrogen, halogen, or oxygen, substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
C07J 17/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
JSTEROIDS
17Normal steroids containing carbon, hydrogen, halogen, or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopentahydrophenanthrene skeleton
CPC
C07J 7/002
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
JSTEROIDS
7Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
0005not substituted in position 21
001substituted in position 20 by a keto group
0015not substituted in position 17 alfa
002not substituted in position 16
C07J 9/005
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
JSTEROIDS
9Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
005containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
C07J 13/007
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
JSTEROIDS
13Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
007with double bond in position 17 (20)
C07J 31/006
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
JSTEROIDS
31Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
006not covered by C07J31/003
C07J 41/0061
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
JSTEROIDS
41Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
0033not covered by C07J41/0005
0055the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
0061one of the carbon atoms being part of an amide group
C07J 13/005
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
JSTEROIDS
13Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
005with double bond in position 16 (17)
Applicants Sage Therapeutics, Inc.
Inventors SALITURO, Francesco, G.
ROBICHAUD, Albert, Jean
MARTINEZ BOTELLA, Gabriel
HARRISON, Boyd, L.
Priority Data 201562189068 P 06.07.2015 US
201662332931 P 06.05.2016 US
Title
(DA) OXYSTEROLER OG FREMGANSMÅDER TIL ANVENDELSE DERFOR
Abstract
(EN) Compounds are provided according to Formula (I) and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof; wherein R1, R2, and R3 are as defined herein. Compounds of the present invention are contemplated useful for the prevention and treatment of a variety of conditions.
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